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伪装成侵袭性真菌性鼻窦炎的眼眶肉芽肿伴多血管炎。

Orbital granulomatosis with polyangiitis masquerading as invasive fungal sinusitis.

作者信息

Xu David, Lin Shawn R, Bonelli Laura, Glasgow Ben J, Goldberg Robert A

机构信息

a Stein Eye Institute, University of California , Los Angeles , CA , USA.

出版信息

Orbit. 2018 Aug;37(4):309-312. doi: 10.1080/01676830.2017.1423339. Epub 2018 Jan 5.

Abstract

A 55-year-old man presented with unilateral orbital inflammation and no light perception vision. Imaging revealed infiltrative enhancement of the optic nerve, orbit, and intracranial tissue. The case was suspicious for invasive fungal disease, but ultimate workup and orbital biopsy revealed granulomatosis with polyangiitis. The patient's inflammation resolved with corticosteroid and rituximab therapy. Granulomatosis with polyangiitis is a systemic vasculitis that can mimic a number of orbital pathologies.

摘要

一名55岁男性出现单侧眼眶炎症且无光感视力。影像学检查显示视神经、眼眶和颅内组织有浸润性强化。该病例怀疑为侵袭性真菌病,但最终的检查和眼眶活检显示为肉芽肿性多血管炎。患者的炎症通过皮质类固醇和利妥昔单抗治疗得以缓解。肉芽肿性多血管炎是一种系统性血管炎,可模仿多种眼眶病变。

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