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电渗作用调制下的微血管非牛顿血流研究。

Study of microvascular non-Newtonian blood flow modulated by electroosmosis.

机构信息

Department of Mechanical Engineering, Manipal University Jaipur, Rajasthan 303007, India.

Department of Mechanical Engineering, Manipal University Jaipur, Rajasthan 303007, India.

出版信息

Microvasc Res. 2018 May;117:28-36. doi: 10.1016/j.mvr.2018.01.001. Epub 2018 Jan 3.

Abstract

An analytical study of microvascular non-Newtonian blood flow is conducted incorporating the electro-osmosis phenomenon. Blood is considered as a Bingham rheological aqueous ionic solution. An externally applied static axial electrical field is imposed on the system. The Poisson-Boltzmann equation for electrical potential distribution is implemented to accommodate the electrical double layer in the microvascular regime. With long wavelength, lubrication and Debye-Hückel approximations, the boundary value problem is rendered non-dimensional. Analytical solutions are derived for the axial velocity, volumetric flow rate, pressure gradient, volumetric flow rate, averaged volumetric flow rate along one time period, pressure rise along one wavelength and stream function. A plug swidth is featured in the solutions. Via symbolic software (Mathematica), graphical plots are generated for the influence of Bingham plug flow width parameter, electrical Debye length and Helmholtz-Smoluchowski velocity (maximum electro-osmotic velocity) on the key hydrodynamic variables. This study reveals that blood flow rate accelerates with decreasing the plug width (i.e. viscoplastic nature of fluids) and also with increasing the Debye length parameter.

摘要

对考虑电渗流现象的微血管非牛顿血流进行分析研究。血液被视为宾汉姆流变学水基离子溶液。在系统上施加外部静态轴向电场。泊松-玻尔兹曼方程用于电势能分布,以适应微血管状态下的双电层。在长波长、润滑和德拜-休克尔近似下,边界值问题被转化为无量纲形式。推导出轴向速度、体积流量、压力梯度、体积流量、沿一个周期的平均体积流量、沿一个波长的压力上升和流函数的解析解。解中具有塞宽特征。通过符号软件(Mathematica)生成图形图,以研究宾汉姆塞流宽度参数、电德拜长度和亥姆霍兹-斯莫卢霍夫斯基速度(最大电渗流速度)对关键流体动力变量的影响。本研究表明,血流速度随塞宽的减小(即流体的粘塑性)而加速,随德拜长度参数的增大而加速。

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