CAS Key Laboratory of Behavioral Science, Institute of Psychology, Beijing, China; Department of Psychology, Tianjin University of Technology and Education, Tianjin, China; University of Chinese Academy of Sciences, Beijing, China.
CAS Key Laboratory of Behavioral Science, Institute of Psychology, Beijing, China; University of Chinese Academy of Sciences, Beijing, China.
Psychoneuroendocrinology. 2018 Mar;89:23-29. doi: 10.1016/j.psyneuen.2017.12.016. Epub 2017 Dec 21.
The cortisol awakening response (CAR) is the rapid increase of cortisol levels 30-45 min after awakening in the morning. Numerous studies have indicated the relationship between the CAR and cognition. However, little is known about daily variation in the CAR and cognitive function in healthy adults. The aim of the present study was to investigate whether the CAR predicted the response inhibition function on the same day in both behaviour and the dynamic time course of brain processing. The saliva samples of 47 healthy men were collected at three time points: immediately on awakening, 30 min and 45 min post-awakening in the morning. Participants performed a Go/NoGo task while electroencephalograms (EEG) were recorded in the afternoon of the same day. The results showed that a greater CAR was associated with a stronger N2. In the sub-group of CAR responders (n = 33) the CAR was negatively related to the false alarm rate of NoGo-trials. Our findings suggested that the CAR was predictive of the function of response inhibition in both the earlier cognitive step (i.e., conflict monitoring) and the behavioural performance of response inhibition on the same day in healthy men.
皮质醇觉醒反应（CAR）是指早晨醒来后 30-45 分钟内皮质醇水平的快速升高。许多研究表明 CAR 与认知之间存在关系。然而，对于健康成年人中 CAR 和认知功能的日常变化知之甚少。本研究旨在探讨 CAR 是否可以预测同一天行为和大脑处理动态时间过程中的反应抑制功能。清晨，47 名健康男性被采集了三个时间点的唾液样本：刚醒来时、醒来后 30 分钟和 45 分钟。参与者在当天下午进行了 Go/NoGo 任务，同时记录了脑电图（EEG）。结果表明，CAR 越大，N2 越强。在 CAR 反应者亚组（n=33）中，CAR 与 NoGo 试验的虚报率呈负相关。我们的研究结果表明，在健康男性中，CAR 可以预测同一天的认知步骤（即冲突监测）和反应抑制行为表现中的反应抑制功能。
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