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伴有残角的瘢痕子宫内膜异位症:一例经组织病理学和免疫组织化学诊断的罕见且具启发性的病例报告

Scar Endometriosis with Rudimentary Horn: An Unusual and Elucidative Report of a Case Diagnosed on Histopathology and Immunohistochemistry.

作者信息

Chauhan Varsha, Pujani Mukta, Singh Kanika, Chawla Raina, Ahuja Rashmi

机构信息

Department of Pathology, ESIC Medical College and Hospital, Faridabad, Haryana, India.

Department of Obstetrics and Gynecology, ESIC Medical College and Hospital, Faridabad, Haryana, India.

出版信息

J Midlife Health. 2017 Oct-Dec;8(4):196-199. doi: 10.4103/jmh.JMH_69_17.

DOI:10.4103/jmh.JMH_69_17
PMID:29307985
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5753504/
Abstract

Endometriosis is defined as the presence of functioning endometrial tissue outside the endometrial cavity. Scar endometriosis, also known as spontaneous abdominal wall endometriosis, is an unusual clinical presentation which often goes unnoticed. It usually develops after pelvic operations. The incidence has been estimated to be only 0.03%-0.15% of all cases of endometriosis. It can be either asymptomatic or present as abdominal wall pain at the site of surgical incision. It is most commonly diagnosed clinically or on ultrasonography. The treatment of choice predominantly remains surgical excision. We present a case of a 24-year-old female (known case of bicornuate uterus) who presented with chief complaints of abdominal pain for 1 month and 6 months after metroplasty. The patient was clinically diagnosed as a case of scar endometriosis with rudimentary horn and fistulous tract and taken up for surgery. Both the scar tissue and fistulous tract were removed and histopathology revealed only endometrial glands without stroma or hemosiderin-laden macrophages. Diagnosis of scar endometriosis was established on positive immunohistochemistry for estrogen and progesterone receptor in endometrial glands. Timely diagnosis and surgical excision of scar endometriosis along with close follow-up are necessary to prevent complications and recurrence.

摘要

子宫内膜异位症定义为子宫内膜腔外存在有功能的子宫内膜组织。瘢痕子宫内膜异位症,也称为自发性腹壁子宫内膜异位症,是一种不常见的临床表现,常被忽视。它通常在盆腔手术后发生。据估计,其发病率仅占所有子宫内膜异位症病例的0.03%-0.15%。它可以无症状,也可表现为手术切口部位的腹壁疼痛。最常见的诊断方法是临床诊断或超声检查。主要的治疗选择仍然是手术切除。我们报告一例24岁女性(双子宫已知病例),因子宫成形术后1个月和6个月出现腹痛为主诉前来就诊。该患者临床诊断为伴有残角和瘘管的瘢痕子宫内膜异位症,并接受了手术治疗。切除了瘢痕组织和瘘管,组织病理学检查仅发现子宫内膜腺体,无基质或含铁血黄素巨噬细胞。通过子宫内膜腺体雌激素和孕激素受体免疫组化阳性确诊为瘢痕子宫内膜异位症。及时诊断和手术切除瘢痕子宫内膜异位症并密切随访对于预防并发症和复发是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9d5/5753504/74c2705ae323/JMH-8-196-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9d5/5753504/50e9ca2596e5/JMH-8-196-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9d5/5753504/74c2705ae323/JMH-8-196-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9d5/5753504/50e9ca2596e5/JMH-8-196-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9d5/5753504/74c2705ae323/JMH-8-196-g002.jpg

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本文引用的文献

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Endometriosis at caesarian section scar.剖宫产瘢痕处子宫内膜异位症
Oman Med J. 2009 Oct;24(4):294-5. doi: 10.5001/omj.2009.59.
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Scar endometriosis - a rare cause for a painful scar: A case report and review of the literature.瘢痕子宫内膜异位症——瘢痕疼痛的罕见病因:一例病例报告及文献综述
Can J Plast Surg. 2010 Spring;18(1):19-20. doi: 10.1177/229255031001800110.
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Extragenital endometriosis--a clinicopathological review of a Glasgow hospital experience with case illustrations.生殖器外子宫内膜异位症——格拉斯哥一家医院经验的临床病理回顾并附病例说明
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Abdominal wall endometriomas near cesarean delivery scars: sonographic and color doppler findings in a series of 12 patients.剖宫产瘢痕附近的腹壁子宫内膜异位症:12例患者的超声及彩色多普勒表现
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