Yang Yanling, Liu Yang, Li Guilin, Li Lei, Geng Peng, Song Hongjuan
Dept. of Gynaecology, Xuzhou Maternal & Child Health Care Hospital, Xuzhou, China.
Iran J Public Health. 2017 Oct;46(10):1332-1337.
We aimed to investigate the effect of vaginal stump ligation in laparoscopic cervical cancer surgery on the prevention of cancer cell detachment.
The study was conducted from 2010 to 2015, in Xuzhou Maternity and Child Health Care Hospital, Jiangsu Province, China. Seventeen cases of laparoscopic surgery of cervical cancer in control group were observed, and the vaginal stump was irrigated with normal saline after the operation and the washing fluid was searched for cancer cells. Moreover, 43 cases of cervical cancer patients received the same operational procedure, and the vaginal stump was ligated in the surgery and the vagina was incised below the ligature.
The number of cancer cells in the vaginal washing fluid of the experimental group was significantly more than that of the control group. Furthermore, there was no significant difference in the operation time, intraoperative blood loss, the number of pelvic lymph node dissected, vaginal resection length and parametrium resection length. By comparing the postoperative recovery indicators and complications, we found no significant difference in anal exsufflation time, the incidence of vaginal stump infection, the recovery time of postoperative urinary function and incidence of lymphocysts. Finally, there was no significant difference in the quality of life scores between the two groups.
Vaginal stump ligation can reduce cancer cell detachment in cervical cancer surgery, and therefore can help preventing cancer cell implantation and tumor recurrence caused by cancer cell detachment.
我们旨在研究腹腔镜宫颈癌手术中阴道残端结扎对预防癌细胞脱落的效果。
该研究于2010年至2015年在中国江苏省徐州市妇幼保健院进行。观察对照组17例腹腔镜宫颈癌手术患者，术后用生理盐水冲洗阴道残端并查找冲洗液中的癌细胞。另外，43例宫颈癌患者接受相同手术操作，术中结扎阴道残端并在结扎下方切开阴道。
实验组阴道冲洗液中癌细胞数量显著多于对照组。此外，两组在手术时间、术中出血量、盆腔淋巴结清扫数量、阴道切除长度和宫旁组织切除长度方面无显著差异。通过比较术后恢复指标和并发症，我们发现两组在肛门排气时间、阴道残端感染发生率、术后排尿功能恢复时间和淋巴囊肿发生率方面无显著差异。最后，两组生活质量评分无显著差异。
阴道残端结扎可减少宫颈癌手术中癌细胞脱落，因此有助于预防因癌细胞脱落导致的癌细胞种植和肿瘤复发。
