He Hai-Lei, Liu Zhong-Long, Ma Chun-Yue, Li Xiao-Guang, He Yue
Department of Stomatology. Ganzhou People's Hospital. Ganzhou 341000, Jiangxi Province, China. E-mail:
Shanghai Kou Qiang Yi Xue. 2017 Oct;26(5):569-572.
To analyze the clinical features, histopathological features, treatment and prognosis of carcinosarcoma in oromaxillofacial head and neck region.
The clinical and histopathological data of 10 cases with carcinosarama were collected from database of Shanghai Ninth People's Hospital and further analyzed.
A total of 10 cases (8 males and 2 females) of carcinosarcoma were collected and analyzed. The age of patients ranged from 20 to 81 years (mean: 44, median:45.5). The tumor size was related to the primary site. The main clinical manifestations indicated rapid increase of foreign body sensation or mass, even feeling of pain. Pathologic examination confirmed the presence of carcinoma and sarcomatoid stroma. Carcinosarcoma had low incidence and was easily misdiagnosed. Diagnosis depended on pathologic examination especially immunohistochemistry. The prognosis was poor, and 5 year survival rate was 50%.
Diagnosis to carcinosarcoma depends on pathological examination after operation. Complete resection + free flap transplantation + postoperative radiotherapy and chemotherapy are conventional treatment.
分析口腔颌面头颈部癌肉瘤的临床特征、组织病理学特征、治疗方法及预后。
从上海第九人民医院数据库中收集10例癌肉瘤患者的临床及组织病理学资料，并进行进一步分析。
共收集并分析了10例癌肉瘤患者（8例男性，2例女性）。患者年龄范围为20至81岁（平均44岁，中位数45.5岁）。肿瘤大小与原发部位有关。主要临床表现为异物感或肿块迅速增大，甚至有疼痛感。病理检查证实存在癌和肉瘤样间质。癌肉瘤发病率低，易误诊。诊断依赖于病理检查，尤其是免疫组化。预后较差，5年生存率为50%。
癌肉瘤的诊断依赖于术后病理检查。完整切除+游离皮瓣移植+术后放疗和化疗是常规治疗方法。
