Department of Orthopaedic Surgery, University of Virginia, Charlottesville, Virginia, USA.
Am J Sports Med. 2018 Mar;46(4):809-814. doi: 10.1177/0363546517749212. Epub 2018 Jan 8.
Shoulder arthroscopy is well established as a highly effective and safe procedure for the treatment for several shoulder disorders and is associated with an exceedingly low risk of infectious complications. Few data exist regarding risk factors for infection after shoulder arthroscopy, as previous studies were not adequately powered to evaluate for infection.
To determine patient-related risk factors for infection after shoulder arthroscopy by using a large insurance database.
Case-control study; Level of evidence, 3.
The PearlDiver patient records database was used to query the 100% Medicare Standard Analytic Files from 2005 to 2014 for patients undergoing shoulder arthroscopy. Patients undergoing shoulder arthroscopy for a diagnosis of infection or with a history of prior infection were excluded. Postoperative infection within 90 days postoperatively was then assessed with International Classification of Diseases, Ninth Revision codes for a diagnosis of postoperative infection or septic shoulder arthritis or a procedure for these indications. A multivariate binomial logistic regression analysis was then utilized to evaluate the use of an intraoperative steroid injection, as well as numerous patient-related risk factors for postoperative infection. Adjusted odds ratios (ORs) and 95% CIs were calculated for each risk factor, with P < .05 considered statistically significant.
A total of 530,754 patients met all inclusion and exclusion criteria. There were 1409 infections within 90 days postoperatively (0.26%). Revision shoulder arthroscopy was the most significant risk factor for infection (OR, 3.25; 95% CI, 2.7-4.0; P < .0001). Intraoperative steroid injection was also an independent risk factor for postoperative infection (OR, 1.46; 95% CI, 1.2-1.9; P = .002). There were also numerous independent patient-related risk factors for infection, the most significant of which were chronic anemia (OR, 1.58; 95% CI, 1.4-1.8; P < .0001), malnutrition (OR, 1.42; 95% CI, 1.2-1.7; P = .001), male sex (OR, 2.71; 95% CI, 2.4-3.1; P < .0001), morbid obesity (OR, 1.41; 95% CI, 1.2-1.6; P < .0001), and depression (OR, 1.36; 95% CI, 1.2-1.5; P < .0001).
Intraoperative steroid injection was a significant independent risk factor for postoperative infection after shoulder arthroscopy. There were also numerous significant patient-related risk factors for postoperative infection, including revision surgery, obesity, male sex, chronic anemia, malnutrition, depression, and alcohol use, among others.
肩关节镜作为一种治疗多种肩部疾病的高效且安全的方法已经得到广泛认可,其术后感染的风险极低。然而,关于肩关节镜术后感染的危险因素,目前仅有少量数据,因为此前的研究并未充分评估感染的风险。
利用大型医疗保险数据库,确定肩关节镜术后感染的患者相关危险因素。
病例对照研究;证据等级 3 级。
使用 PearlDiver 患者记录数据库,从 2005 年至 2014 年查询 Medicare 标准分析文件的 100%数据,纳入接受肩关节镜手术的患者。排除诊断为感染或有既往感染史的患者。术后 90 天内发生的感染通过国际疾病分类第 9 版的术后感染或化脓性肩关节炎或这些适应证的手术进行评估。然后利用二元逻辑回归分析评估术中类固醇注射以及与术后感染相关的多种患者相关危险因素的使用情况。对于每个危险因素,计算调整后的优势比(OR)和 95%置信区间(CI),P<.05 认为具有统计学意义。
共纳入 530754 名符合所有纳入和排除标准的患者。术后 90 天内发生 1409 例感染(0.26%)。翻修肩关节镜是感染的最显著危险因素(OR,3.25;95%CI,2.7-4.0;P<.0001)。术中类固醇注射也是术后感染的独立危险因素(OR,1.46;95%CI,1.2-1.9;P=0.002)。此外,还有许多与患者相关的感染独立危险因素,其中最重要的是慢性贫血(OR,1.58;95%CI,1.4-1.8;P<.0001)、营养不良(OR,1.42;95%CI,1.2-1.7;P=0.001)、男性(OR,2.71;95%CI,2.4-3.1;P<.0001)、病态肥胖(OR,1.41;95%CI,1.2-1.6;P<.0001)和抑郁(OR,1.36;95%CI,1.2-1.5;P<.0001)。
术中类固醇注射是肩关节镜术后感染的一个显著独立危险因素。还有许多与患者相关的感染的独立危险因素,包括翻修手术、肥胖、男性、慢性贫血、营养不良、抑郁和饮酒等。