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本文引用的文献

1
Implant-Related Complications Among Patients With Opioid Use Disorder Following Primary Total Hip Arthroplasty: A Matched-Control Analysis of 42,097 Medicare Patients.在初次全髋关节置换术后患有阿片类药物使用障碍的患者中,与植入物相关的并发症:42097 名医疗保险患者的匹配对照分析。
J Arthroplasty. 2020 Jan;35(1):178-181. doi: 10.1016/j.arth.2019.08.003. Epub 2019 Aug 7.
2
Opioid Disorders Are Associated With Thromboemboli Following Primary Total Knee Arthroplasty.原发性全膝关节置换术后,阿片类药物使用障碍与血栓栓塞有关。
J Arthroplasty. 2019 Dec;34(12):2957-2961. doi: 10.1016/j.arth.2019.07.042. Epub 2019 Aug 3.
3
Elective Shoulder Surgery in the Opioid Naïve: Rates of and Risk Factors for Long-term Postoperative Opioid Use.择期肩关节手术在阿片类药物初治患者中的应用:长期术后阿片类药物使用的发生率和危险因素。
Am J Sports Med. 2019 Apr;47(5):1051-1056. doi: 10.1177/0363546519837516.
4
The impact of preoperative opioid use on outcomes after arthroscopic rotator cuff repair.术前使用阿片类药物对关节镜下肩袖修复术后结局的影响。
JSES Open Access. 2018 Jun 21;2(3):155-158. doi: 10.1016/j.jses.2018.05.001. eCollection 2018 Oct.
5
Trends in cervical disc arthroplasty and revisions in the Medicare database.医疗保险数据库中颈椎间盘置换术及翻修术的趋势
J Spine Surg. 2018 Sep;4(3):522-528. doi: 10.21037/jss.2018.09.04.
6
Preoperative Opioids Increase the Risk of Periprosthetic Joint Infection After Total Joint Arthroplasty.术前使用阿片类药物会增加全膝关节置换术后假体周围关节感染的风险。
J Arthroplasty. 2018 Oct;33(10):3246-3251.e1. doi: 10.1016/j.arth.2018.05.027. Epub 2018 May 29.
7
Healthcare costs and utilization associated with high-risk prescription opioid use: a retrospective cohort study.与高风险处方类阿片类药物使用相关的医疗保健费用和利用:一项回顾性队列研究。
BMC Med. 2018 May 16;16(1):69. doi: 10.1186/s12916-018-1058-y.
8
Preoperative Chronic Opioid Therapy: A Risk Factor for Complications, Readmission, Continued Opioid Use and Increased Costs After One- and Two-Level Posterior Lumbar Fusion.术前慢性阿片类药物治疗:在进行一到两节后路腰椎融合术后,是并发症、再入院、持续阿片类药物使用和增加成本的风险因素。
Spine (Phila Pa 1976). 2018 Oct 1;43(19):1331-1338. doi: 10.1097/BRS.0000000000002609.
9
Opioid Abuse or Dependence Increases 30-day Readmission Rates after Major Operating Room Procedures: A National Readmissions Database Study.阿片类药物滥用或依赖会增加大手术术后 30 天的再入院率:一项全国再入院数据库研究。
Anesthesiology. 2018 May;128(5):880-890. doi: 10.1097/ALN.0000000000002136.
10
Risk Factors for Infection After Shoulder Arthroscopy in a Large Medicare Population.在大型医疗保险人群中,肩关节镜术后感染的危险因素。
Am J Sports Med. 2018 Mar;46(4):809-814. doi: 10.1177/0363546517749212. Epub 2018 Jan 8.

接受初次肩关节置换术的阿片类药物使用障碍患者的植入物相关并发症:一项配对对照分析。

Implant-related complications in patients with opioid use disorder undergoing primary shoulder arthroplasties: a matched-controlled analysis.

作者信息

Swiggett Samuel J, Ciminero Matthew L, Weisberg Miriam D, Vakharia Rushabh M, Sadeghpour Ramin, Choueka Jack

机构信息

Department of Orthopaedic Surgery, Maimonides Medical Center, Brooklyn, NY, USA.

出版信息

Shoulder Elbow. 2022 Aug;14(4):395-401. doi: 10.1177/1758573221994790. Epub 2021 Mar 2.

DOI:10.1177/1758573221994790
PMID:35846397
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9284306/
Abstract

BACKGROUND

The purpose of this study was to investigate whether patients undergoing primary shoulder arthroplasty with opioid use disorder have higher rates of (1) implant-related complications; (2) in-hospital lengths of stay; (3) readmission rates; and (4) costs of care.

METHODS

Opioid use disorder patients undergoing primary shoulder arthroplasty were queried and matched in a 1:5 ratio to controls by age, sex, and medical comorbidities within the Medicare database. The query yielded 25,489 patients with ( = 4253) and without ( = 21,236) opioid use disorder. Primary outcomes analyzed included: 2-year implant related complications, in-hospital lengths of stay, 90-day readmission rates, and 90-day costs of care. A value less than 0.01 was considered statistically significant.

RESULTS

Opioid use disorder patients had significantly longer in-hospital lengths of stay (3 days vs. 2 days; 0.0001) compared to matched controls. Opioid use disorder patients were also found to have higher incidence and odds (OR) of readmission rates (12.84 vs. 7.45%; OR: 1.16, 0.0001) and implant-related complications (20.03 vs. 7.95%; OR: 1.82, 0.0001). Study group patients also incurred significantly higher 90-day costs of care ($16,918.85 vs. $15,195.37, 0.0001).

DISCUSSION

This study can be used to help further augment efforts to reduce opioid prescriptions from healthcare providers in shoulder arthroplasty settings.

摘要

背景

本研究的目的是调查患有阿片类药物使用障碍的初次肩关节置换术患者是否有更高的(1)植入物相关并发症发生率;(2)住院时间;(3)再入院率;以及(4)护理费用。

方法

在医疗保险数据库中,对患有阿片类药物使用障碍的初次肩关节置换术患者进行查询,并按年龄、性别和合并症以1:5的比例与对照组进行匹配。该查询产生了25489名患者,其中有(n = 4253)和没有(n = 21236)阿片类药物使用障碍。分析的主要结果包括:2年植入物相关并发症、住院时间、90天再入院率和90天护理费用。p值小于0.01被认为具有统计学意义。

结果

与匹配的对照组相比,患有阿片类药物使用障碍的患者住院时间明显更长(3天对2天;p = 0.0001)。还发现患有阿片类药物使用障碍的患者再入院率的发生率和比值比(OR)更高(12.84%对7.45%;OR:1.16,p = 0.0001)以及植入物相关并发症(2​​0.03%对7.95%;OR:1.82,p = 0.0001)。研究组患者的90天护理费用也明显更高(16918.85美元对15195.37美元,p = 0.0001)。

讨论

本研究可用于帮助进一步加大力度,减少医疗保健提供者在肩关节置换术中开具阿片类药物的处方。