Singhania Sumeet Vimal Kishor, Parikh Pujan, Goyle Sandeep
Consultant, Pulmonary Medicine.
Clinical Assistant, Pulmonary Medicine.
J Assoc Physicians India. 2017 Sep;65(9):92-93.
Bendamustine has been increasingly used for treatment of indolent lymphoma for the past few years. The data on safety profile of this drug is still emerging with the increasing use of this drug. The higher occurrence of CMV reactivation with this drug has been reported in few case reports only. We report a case of CMV penumonitis initially presenting as unexplained pyrexia which responded well to intravenous Ganciclovir. This case report re-iterates the suspicion of CMV reactivation in lymphoma patients receiving bendamustine who present with unexplained pyrexia or chest symptoms.
在过去几年中,苯达莫司汀越来越多地用于惰性淋巴瘤的治疗。随着这种药物使用的增加,关于其安全性的数据仍在不断涌现。仅在少数病例报告中报道了该药物导致巨细胞病毒(CMV)再激活的发生率较高。我们报告了一例CMV肺炎病例,最初表现为不明原因发热,静脉注射更昔洛韦后反应良好。本病例报告再次强调,对于接受苯达莫司汀治疗且出现不明原因发热或胸部症状的淋巴瘤患者,应怀疑CMV再激活。