Mascagni Pietro, Melandro Fabio, Larghi Laureiro Zoe, Mennini Gianluca, Rossi Massimo
Dipartimento di Chirurgia Generale e Specialistica, Azienda Ospedaliera Policlinico Umberto I, Italia.
Dipartimento di Chirurgia Generale e Specialistica, Azienda Ospedaliera Policlinico Umberto I.
Rev Esp Enferm Dig. 2018 Apr;110(4):254-256. doi: 10.17235/reed.2017.5103/2017.
This article is the first description of a spontaneous hepatic rupture in a young bodybuilder with a history of clenbuterol and ephedrine alkaloid use. The patient presented with a sudden mid-epigastric pain and vomiting. Hemoglobin levels decreased a few hours later and a computed tomography scan was performed which revealed a rupture of the right liver capsule and hemoperitoneum. Two attempts at transarterial embolization did not control the bleeding and a right hemihepatectomy was performed. The pathological report identified a hepatic adenoma, a capsular tear and diffuse peliosis hepatis. The patient was discharged in a good condition after eleven days. Spontaneous hepatic ruptures are rare and life-threatening and are usually described in association with tumors, connective tissue diseases and gestosis. This article is a review of the available literature with regard to this condition, with a focus on its relation to peliosis hepatis and banned substance used by body image fanatics. The present case highlights the challenging diagnosis of this potentially fatal liver complication in a healthy appearing male, the risk associated with the online trade of performance enhancing drugs and its relation with peliosis hepatis.
本文首次描述了一名有使用克仑特罗和麻黄碱类生物碱病史的年轻健美运动员发生的自发性肝破裂。患者表现为突发上腹部中部疼痛和呕吐。数小时后血红蛋白水平下降,随后进行了计算机断层扫描,结果显示右肝包膜破裂和腹腔积血。两次经动脉栓塞术均未能控制出血,遂行右半肝切除术。病理报告显示为肝腺瘤、包膜撕裂和弥漫性肝紫癜。患者在十一天后康复出院。自发性肝破裂很少见且危及生命,通常与肿瘤、结缔组织疾病和妊娠中毒症有关。本文是关于这种情况的现有文献综述,重点关注其与肝紫癜以及身体塑形爱好者使用违禁物质的关系。本病例突出了在看似健康的男性中诊断这种潜在致命性肝脏并发症的挑战性、与增强运动表现药物网络交易相关的风险及其与肝紫癜的关系。