免疫学：黏膜免疫的神经途径。

Immunology: The Neuronal Pathway to Mucosal Immunity.

机构信息

Wellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, College of Medical, Veterinary & Life Sciences, University of Glasgow, 120 University Place, Glasgow G12 8TA, UK.

出版信息

Curr Biol. 2018 Jan 8;28(1):R33-R36. doi: 10.1016/j.cub.2017.11.025.

DOI:10.1016/j.cub.2017.11.025

PMID:29316420

Abstract

Type 2 immunity at mucosal surfaces is thought to be initiated by type 2 innate lymphoid cells. New studies report that these cells are themselves activated by the neuropeptide neuromedin U, produced by cholinergic neurons in the gut and in airways.

摘要

人们认为 2 型免疫发生在黏膜表面，是由 2 型先天淋巴样细胞启动的。新的研究报告称，这些细胞本身被肠道和气道中的胆碱能神经元产生的神经肽神经调节素 U 激活。