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随机缩短牙弓研究:10年牙齿缺失情况

The Randomized Shortened Dental Arch Study: Tooth Loss Over 10 Years.

作者信息

Walter Michael H, Dreyhaupt Jens, Hannak Wolfgang, Wolfart Stefan, Luthardt Ralph G, Stark Helmut, Pospiech Peter, Mundt Torsten, Kern Matthias, Böning Klaus Walter, Wöstmann Bernd, Scheller Herbert, Jahn Florentine, Reinhardt Wilfried, Strub Joerg, Marré Birgit, Heydecke Guido

出版信息

Int J Prosthodont. 2018 Jan/Feb;31(1):77-84. doi: 10.11607/ijp.5368.

Abstract

PURPOSE

This study aimed to compare the long-term outcomes of two different nonimplant treatments in the bilateral shortened dental arch (SDA).

MATERIALS AND METHODS

In a multicenter randomized controlled clinical trial, patients with complete molar loss in one arch were assigned to one of two different nonimplant treatments. In the partial removable dental prosthesis (PRDP) group, patients were provided with a distal-extension prosthesis retained with precision attachments. In the SDA group, patients were treated according to the SDA concept by preserving or restoring a premolar occlusion.

RESULTS

Of the 152 treated patients, 82 reached the 10-year examination independent of their dental or prosthetic status. In the intention-to-treat analysis, the survival rates for tooth loss at 10 years were 0.44 (95% confidence interval [CI]: 0.30 to 0.56) in the PRDP group and 0.52 (95% CI: 0.37 to 0.65) in the SDA group. For tooth loss in the study arch, the survival rates were 0.67 (95% CI: 0.52 to 0.78) in the PRDP group and 0.60 (95% CI: 0.45 to 0.73) in the SDA group. The number of teeth lost was higher than expected. In a multivariate analysis using a multiple Cox regression model, the covariates age (unit: 1 year, Hazard Ratio [HR]: 1.033, P = .03) and DMFT value (unit: 1 tooth, HR: 1.121, P = .03) were significant for time to first tooth loss in the study arch.

CONCLUSION

The results suggest an overestimation of the influence of the prosthetic management of the bilateral SDA. In treatment decisions, patient preferences should be considered with appropriate weight.

摘要

目的

本研究旨在比较两种不同的非种植治疗方法对双侧短牙弓(SDA)的长期疗效。

材料与方法

在一项多中心随机对照临床试验中,一侧牙弓磨牙全部缺失的患者被分配至两种不同的非种植治疗方法之一。在局部可摘义齿(PRDP)组,为患者提供带有精密附着体的远中游离端义齿。在SDA组,根据SDA理念,通过保留或恢复前磨牙咬合来治疗患者。

结果

152例接受治疗的患者中,82例患者无论其牙齿或修复体状况如何均接受了10年检查。在意向性分析中,PRDP组10年牙齿缺失生存率为0.44(95%置信区间[CI]:0.30至0.56),SDA组为0.52(95%CI:0.37至0.65)。对于研究牙弓中的牙齿缺失,PRDP组生存率为0.67(95%CI:0.52至0.78),SDA组为0.60(95%CI:0.45至0.73)。牙齿缺失数量高于预期。在使用多重Cox回归模型的多变量分析中,协变量年龄(单位:1岁,风险比[HR]:1.033,P = .03)和DMFT值(单位:1颗牙,HR:1.121,P = .03)对研究牙弓中首次牙齿缺失时间具有显著意义。

结论

结果表明对双侧SDA修复治疗影响的估计过高。在治疗决策中,应适当权衡考虑患者的偏好。

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