Tauziède-Espariat Arnault, Chrétien Fabrice, Jouvion Grégory, Alde-Biassette Homa, Hofman Paul
Laboratoire de neuropathologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France.
Laboratoire de neuropathologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France; Unité d'histopathologie humaine et modèles animaux, Institut Pasteur, 25-28, rue du Docteur-Roux, 75015 Paris, France.
Ann Pathol. 2018 Feb;38(1):55-63. doi: 10.1016/j.annpat.2017.12.002. Epub 2018 Jan 7.
Pathologists have been, are and will be always implicated in the diagnosis of infectious and tropical diseases. The resurgence of opportunistic infections due to the development of immunosuppressive drugs, the increase of migratory involvements draining tropical infections and the last epidemics spotlight the importance of pathologists in the field of infectious diseases. However, cancer is nowadays the first preoccupation of pathologists, which is constantly subject to evaluate diagnostic and prognostic markers and factors predictive to targeted therapy response or immunotherapy. As tumor pathology, infectious diseases require more sophisticated and rapidly changing complementary techniques, appraisals and perhaps a national network of diagnosis. The infectious pathology club committee carries out here a census of methods used in the diagnosis of infectious diseases in France in 2015 and particularly the different techniques used by laboratories to perform infectious diseases diagnosis. This will lay down the foundation of a future national organization of the infectious pathology in providing efficient services (diagnostic support, complementary tools) for the community of French pathologists in this specific domain of competence.
病理学家过去、现在乃至将来都一直参与传染病和热带病的诊断工作。免疫抑制药物的发展导致机会性感染的再度流行,热带感染引发的移民潮增加,以及近期的疫情,都凸显了病理学家在传染病领域的重要性。然而,如今癌症是病理学家首要关注的问题,他们不断评估诊断和预后标志物以及预测靶向治疗反应或免疫治疗的因素。作为肿瘤病理学,传染病需要更复杂且迅速变化的辅助技术、评估方法,或许还需要一个全国性的诊断网络。传染病病理学俱乐部委员会在此对2015年法国传染病诊断所使用的方法进行普查,特别是各实验室用于进行传染病诊断的不同技术。这将为未来全国性的传染病病理学组织奠定基础,以便在这一特定专业领域为法国病理学家群体提供高效服务(诊断支持、辅助工具)。