Myslivecek J
Physiol Bohemoslov. 1985;34(3):235-45.
With the method of a simple automatic rectangular maze the development of escape reaction was studied in albino rats aged 3 weeks to 3 months as well as memory retrieval within 24 h and then after one month. Learning of escape improves sharply between the 3rd and 4th postnatal week, and then, with the exception of week 8, remains approximately on the same level. Memory retrieval up to 24 h is not significantly influenced by age or sex, but is best immediately after learning interval of 10 min and the poorest after 24 h, except the age of 5 weeks, where it is best in 3 and 6 h after learning. One-month retention of maze escape improves during development except in animals trained at the age of 6 weeks in which the level is lower than in all other investigated groups. One-month memory retrieval in animals taught at the age of 4 weeks is influenced by the time of the first retention test with the best values in animals tested for the first time after 3 h and poorest in animals tested after 24 h after learning. Animals trained at 5 weeks had a marginally better result after the one-month retention test in females, perhaps due to the influence of sexual maturation on memory traces. This was not observed in the other age groups. Attention is drawn to the different development of learning and memory of various types of conditioned reactions stemming from the difference in their complexity.
采用简单的自动矩形迷宫方法，研究了3周龄至3月龄白化大鼠逃避反应的发展以及24小时内和1个月后的记忆恢复情况。出生后第3周和第4周之间，逃避学习能力急剧提高，然后，除了第8周外，大致保持在同一水平。24小时内的记忆恢复不受年龄或性别的显著影响，但在学习间隔10分钟后立即恢复效果最佳，24小时后最差，5周龄除外，5周龄大鼠在学习后3小时和6小时恢复效果最佳。迷宫逃避的1个月保持能力在发育过程中有所提高，但6周龄训练的动物除外，其水平低于所有其他研究组。4周龄训练的动物1个月后的记忆恢复受首次保持测试时间的影响，学习后3小时首次测试的动物恢复效果最佳，学习后24小时测试的动物恢复效果最差。5周龄训练的动物在1个月保持测试后，雌性的结果略好，这可能是由于性成熟对记忆痕迹的影响。在其他年龄组中未观察到这种情况。由于各种条件反应的复杂性不同，请注意它们学习和记忆的不同发展情况。
