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经阴道内镜手术初始浸润肌层治疗子宫内膜癌保留生育功能:一项初步研究。

Fertility-Sparing Treatment of Endometrial Cancer with Initial Infiltration of Myometrium by Resectoscopic Surgery: A Pilot Study.

机构信息

Department of Obstetrics, Gynecology, and Reproductive Biology, University Alma Mater Studiorum of Bologna, Bologna, Italy.

Department of Obstetrics, Gynecology, and Reproductive Biology, University Alma Mater Studiorum of Bologna, Bologna, Italy

出版信息

Oncologist. 2018 Apr;23(4):478-480. doi: 10.1634/theoncologist.2017-0285. Epub 2018 Jan 9.

Abstract

Three women with a well-differentiated grade 1 endometrioid adenocarcinoma of the endometrium with minimal myometrial infiltration were treated with hysteroscopic resection and hormone therapy. The presence of myometrial infiltration has often been mentioned as an exclusion criterion for conservative management in young patients because of worsening cancer prognosis. The subsequent 5-year follow-up and the pregnancies achieved may confirm the choice of this temporary treatment and indicate a new option for fertility-sparing treatment in highly motivated patients.

摘要

三位患有分化良好的子宫内膜 1 级子宫内膜样腺癌且肌层浸润极小的女性患者接受了宫腔镜切除术和激素治疗。肌层浸润的存在通常被认为是年轻患者保守治疗的排除标准,因为这会导致癌症预后恶化。随后的 5 年随访和成功妊娠可能证实了这种临时治疗方案的选择,并为高意愿患者提供了一种新的保留生育力治疗选择。

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