高剂量维生素C输注对一名葡萄糖-6-磷酸脱氢酶缺乏患者的影响。
Effect of High-Dose Vitamin C Infusion in a Glucose-6-Phosphate Dehydrogenase-Deficient Patient.
作者信息
Quinn Joseph, Gerber Bryan, Fouche Ryan, Kenyon Katharine, Blom Zachary, Muthukanagaraj Purushothaman
机构信息
Departments of Emergency Medicine, Internal Medicine, and Critical Care Medicine, East Carolina University, Greenville, NC, USA.
Departments of Emergency Medicine and Internal Medicine, East Carolina University, Greenville, NC, USA.
出版信息
Case Rep Med. 2017;2017:5202606. doi: 10.1155/2017/5202606. Epub 2017 Nov 26.
Abstract
Vitamin C supplementation is generally regarded as benign. There has been a resurgence of interest in the general medical community regarding the use of vitamin C most notably in the care of sepsis. Nonetheless, caution must be taken if supraphysiologic vitamin C supplementation is being administered as it should be considered a medication just like any other. We present a case of hemolysis in a glucose-6-phosphate dehydrogenase- (G6PD-) deficient patient receiving high-dose vitamin C infusions for his rheumatoid arthritis.
摘要
补充维生素C通常被认为是安全无害的。在普通医学界，人们对使用维生素C的兴趣再度兴起，尤其是在脓毒症的治疗方面。然而，如果给予超生理剂量的维生素C补充剂，必须谨慎，因为它应被视为与其他任何药物一样的药物。我们报告一例葡萄糖-6-磷酸脱氢酶（G6PD）缺乏的患者，因类风湿关节炎接受高剂量维生素C输注后发生溶血的病例。
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