Holland Peter
Department of Zoology, University of Oxford, UK.
Int J Dev Biol. 2017;61(10-11-12):585-590. doi: 10.1387/ijdb.170114ph.
The cloning and embryonic expression analysis of an amphioxus Hox gene in 1992 marked the start of molecular analysis of cephalochordate development. Other papers quickly followed, including a description of the amphioxus Hox gene cluster in 1994, fuelling a resurgence of interest in a long-forgotten animal. I describe the academic background, laboratory experiments and field work leading to the earliest publications in amphioxus molecular developmental biology and explain their scientific impact. The story of amphioxus biology in the 1990s involved collaboration, team work, opportunistic meetings, serendipity, incredulous journal editors, stingrays, airport departure lounges and popcorn.
1992年文昌鱼Hox基因的克隆及胚胎表达分析标志着头索动物发育分子分析的开端。随后很快又有其他论文发表，包括1994年对文昌鱼Hox基因簇的描述，这重新燃起了人们对这种被遗忘已久的动物的兴趣。我讲述了促成文昌鱼分子发育生物学最早一批出版物的学术背景、实验室实验和实地研究工作，并解释了它们的科学影响。20世纪90年代文昌鱼生物学的故事涉及合作、团队协作、机缘巧合的会面、意外发现、持怀疑态度的期刊编辑、黄貂鱼、机场候机室和爆米花。
