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Cancer statistics, 2016.癌症统计数据,2016 年。
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Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial.英国卵巢癌筛查协作试验(UKCTOCS)中的卵巢癌筛查与死亡率:一项随机对照试验
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Sexual activity and functioning after risk-reducing salpingo-oophorectomy: Impact of hormone replacement therapy.风险降低型输卵管卵巢切除术(RRSO)后性生活和性功能:激素替代疗法的影响。
Gynecol Oncol. 2016 Jan;140(1):101-6. doi: 10.1016/j.ygyno.2015.11.016. Epub 2015 Nov 18.
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Decision aids for people facing health treatment or screening decisions.为面临医疗治疗或筛查决策的人们提供的决策辅助工具。
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The impact of risk-reducing gynaecological surgery in premenopausal women at high risk of endometrial and ovarian cancer due to Lynch syndrome.降低风险的妇科手术对因林奇综合征而患子宫内膜癌和卵巢癌风险较高的绝经前女性的影响。
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The loss of a mother and dealing with genetic cancer risk: women who have undergone prophylactic removal of the ovaries.失去母亲与应对遗传性癌症风险:接受过预防性卵巢切除的女性。
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Maximising survival: the main concern of women with hereditary breast and ovarian cancer who undergo genetic testing for BRCA1/2.最大限度提高生存率:进行 BRCA1/2 基因检测的遗传性乳腺癌和卵巢癌女性的主要关注点。
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Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation.BRCA1 或 BRCA2 基因突变女性行卵巢切除术对癌症发病率和死亡率的影响。
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Patient Educ Couns. 2014 Mar;94(3):291-309. doi: 10.1016/j.pec.2013.10.031. Epub 2013 Nov 9.

选择预防性卵巢切除术以预防癌症的女性独特的心理和社会经历。

Distinctive psychological and social experiences of women choosing prophylactic oophorectomy for cancer prevention.

作者信息

Meadows Rachel, Padamsee Tasleem J, Paskett Electra D

机构信息

a Division of Epidemiology, College of Public Health, Comprehensive Cancer Center , the Ohio State University , Columbus , Ohio , USA.

b Division of Health Services Management and Policy, College of Public Health, Comprehensive Cancer Center , The Ohio State University , Columbus , Ohio , USA.

出版信息

Health Care Women Int. 2018 May;39(5):595-616. doi: 10.1080/07399332.2018.1424855. Epub 2018 Feb 2.

DOI:10.1080/07399332.2018.1424855
PMID:29319429
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6082146/
Abstract

Women known to have significantly elevated ovarian cancer risk due to genetic mutations or family history can reduce this risk by surgically removing both ovaries and fallopian tubes (RRBSO, risk-reducing bilateral salpingo-oophorectomy). We used interpretive phenomenological analysis (IPA) to explore the psychosocial experiences of women who chose RRBSO for cancer prevention. We extended the traditional use of IPA to compare the experiences of women who chose RRBSO for cancer prevention to those of women who underwent similar gynecologic surgery for benign indications. The analysis resulted in three superordinate themes describing women's psychosocial experiences related to RRBSO: (a) psychological facets of cancer risk (b) social support and (c) shared medical decision making. Findings illustrate that women choosing RRBSO for cancer prevention experience heightened psychosocial challenges before and after surgery compared to women undergoing surgery for benign indication. Furthermore, they may need distinct types of information and support from healthcare providers.

摘要

已知因基因突变或家族病史而卵巢癌风险显著升高的女性,可以通过手术切除双侧卵巢和输卵管(RRBSO,降低风险的双侧输卵管卵巢切除术)来降低这种风险。我们采用解释现象学分析(IPA)来探究选择RRBSO进行癌症预防的女性的心理社会经历。我们扩展了IPA的传统用途,将选择RRBSO进行癌症预防的女性的经历与因良性指征接受类似妇科手术的女性的经历进行比较。分析得出了三个描述女性与RRBSO相关的心理社会经历的上位主题:(a)癌症风险的心理层面;(b)社会支持;(c)共同的医疗决策。研究结果表明,与因良性指征接受手术的女性相比,选择RRBSO进行癌症预防的女性在手术前后经历了更大的心理社会挑战。此外,她们可能需要医疗服务提供者提供不同类型的信息和支持。