Bojinović-Rodić Dragana, Popović-Petrović Svetlana, Tomić Sanja, Markez Stanislava, Živanić Dobrinka
Vojnosanit Pregl. 2016 Sep;73(9):825-30. doi: 10.2298/VSP150208075B.
BACKGROUND/AIM: Upper limb lymphedema is one of the most frequent chronic complications after breast cancer treatment with a significant impact on the upper extremity function and quality of life (QoL). The aim of this study was to estimate health-related quality of life (HRQoL) in patients with breast-cancer-related lymphedema and its correlation with upper limb function and the size of edema.
The cross-sectional study included 54 breast-cancer-related lymphedema patients. The quality of life was evaluated by the Short Form 36-Item Health Survey (SF-36). Upper limb function was assessed by the Quick Disability of the Arm, Shoulder and Hand questionnaire (Quick DASH). The size of lymphedema was determined by the arm circumference.
The higher HRQoL score was assessed for mental health (47.0 ± 12.2) than for physical one (42.2 ± 7.5). The highest values of SF-36 were found in the domains of Mental Health (67.7 ± 22.9) and Social Function (70.1 ± 23.1). The lowest scores were registered in the domains of Role Physical (46.9 ± 39.1) and General Health (49.3 ± 20.1). Upper extremity function statistically significantly correlated with the domains Role Physical, Bodily Pain and Physical Composite Summary and also, with the domain Role Emotional (p < 0.01). There was no statistically significant correlation between size of lymphedema and tested domains of quality of life (p > 0.05).
Physical disability in patients with breast cancer-related lymphedema influences quality of life more than mental health. Upper limb function has a significant impact on quality of life, not only on the physical, but also on the mental component. The presence of breast-cancer-related lymphedema certainly affects upper limb function and quality of life, but in this study no significant correlation between the size of edema and quality of life was found.
背景/目的：上肢淋巴水肿是乳腺癌治疗后最常见的慢性并发症之一，对上肢功能和生活质量（QoL）有重大影响。本研究的目的是评估乳腺癌相关淋巴水肿患者的健康相关生活质量（HRQoL）及其与上肢功能和水肿大小的相关性。
横断面研究纳入了54例乳腺癌相关淋巴水肿患者。生活质量通过简短36项健康调查（SF-36）进行评估。上肢功能通过手臂、肩部和手部快速残疾问卷（Quick DASH）进行评估。淋巴水肿的大小通过手臂周长确定。
心理健康方面的HRQoL评分（47.0±12.2）高于身体方面（42.2±7.5）。SF-36得分最高的领域是心理健康（67.7±22.9）和社会功能（70.1±23.1）。得分最低的领域是角色身体（46.9±39.1）和总体健康（49.3±20.1）。上肢功能与角色身体、身体疼痛和身体综合总结领域以及角色情感领域在统计学上显著相关（p<0.01）。淋巴水肿大小与所测试的生活质量领域之间没有统计学上的显著相关性（p>0.05）。
乳腺癌相关淋巴水肿患者的身体残疾对生活质量的影响大于心理健康。上肢功能不仅对身体，而且对心理成分的生活质量都有重大影响。乳腺癌相关淋巴水肿的存在肯定会影响上肢功能和生活质量，但在本研究中未发现水肿大小与生活质量之间存在显著相关性。
