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Diallyl disulfide down-regulates calreticulin and promotes C/EBPα expression in differentiation of human leukaemia cells.二烯丙基二硫下调钙网蛋白并促进人白血病细胞分化中的 C/EBPα 表达。
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Gemtuzumab ozogamicin for treatment of newly diagnosed CD33-positive acute myeloid leukemia.吉妥珠单抗奥佐米星治疗新诊断的 CD33 阳性急性髓系白血病。
Future Oncol. 2018 Dec;14(30):3199-3213. doi: 10.2217/fon-2018-0325. Epub 2018 Jul 24.

本文引用的文献

1
CD33 Splicing Polymorphism Determines Gemtuzumab Ozogamicin Response in De Novo Acute Myeloid Leukemia: Report From Randomized Phase III Children's Oncology Group Trial AAML0531.CD33剪接多态性决定初治急性髓系白血病中吉妥珠单抗奥唑米星的疗效：儿童肿瘤协作组III期随机试验AAML0531的报告
J Clin Oncol. 2017 Aug 10;35(23):2674-2682. doi: 10.1200/JCO.2016.71.2513. Epub 2017 Jun 23.
2
Consistent quantitative gene product expression: #3. Invariance with age.一致的定量基因产物表达：#3. 随年龄不变。
Cytometry A. 2016 Nov;89(11):997-1000. doi: 10.1002/cyto.a.22997. Epub 2016 Oct 18.
3
Consistent quantitative gene product expression: #2. Antigen intensities on bone marrow cells are invariant between individuals.一致的定量基因产物表达：#2. 骨髓细胞上的抗原强度在个体之间是不变的。
Cytometry A. 2016 Nov;89(11):987-996. doi: 10.1002/cyto.a.22999. Epub 2016 Oct 18.
4
Consistent quantitative gene product expression: #1. Automated identification of regenerating bone marrow cell populations using support vector machines.一致的定量基因产物表达：#1. 使用支持向量机自动识别再生骨髓细胞群体。
Cytometry A. 2016 Nov;89(11):978-986. doi: 10.1002/cyto.a.22905. Epub 2016 Jul 14.
5
CD33 Expression and Its Association With Gemtuzumab Ozogamicin Response: Results From the Randomized Phase III Children's Oncology Group Trial AAML0531.CD33表达及其与吉妥珠单抗奥唑米星反应的关联：儿童肿瘤学组III期随机试验AAML0531的结果
J Clin Oncol. 2016 Mar 1;34(7):747-55. doi: 10.1200/JCO.2015.62.6846. Epub 2016 Jan 19.
6
Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.阿尔茨海默病和急性髓系白血病中CD33的遗传学
Hum Mol Genet. 2015 Jun 15;24(12):3557-70. doi: 10.1093/hmg/ddv092. Epub 2015 Mar 11.
7
Gemtuzumab ozogamicin in children and adolescents with de novo acute myeloid leukemia improves event-free survival by reducing relapse risk: results from the randomized phase III Children’s Oncology Group trial AAML0531.吉妥单抗奥唑米星用于初治急性髓系白血病儿童和青少年可通过降低复发风险提高无事件生存期：儿童肿瘤学组III期随机试验AAML0531的结果
J Clin Oncol. 2014 Sep 20;32(27):3021-32. doi: 10.1200/JCO.2014.55.3628.
8
CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility.CD33：外显子2包含增加表明免疫球蛋白V区结构域与阿尔茨海默病易感性有关。
Hum Mol Genet. 2014 May 15;23(10):2729-36. doi: 10.1093/hmg/ddt666. Epub 2013 Dec 30.
9
CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing.CD33 阿尔茨海默病风险改变多态性、CD33 表达和外显子 2 剪接。
J Neurosci. 2013 Aug 14;33(33):13320-5. doi: 10.1523/JNEUROSCI.1224-13.2013.
10
Clinical significance of CD33 nonsynonymous single-nucleotide polymorphisms in pediatric patients with acute myeloid leukemia treated with gemtuzumab-ozogamicin-containing chemotherapy.CD33 非同义单核苷酸多态性在接受含吉妥珠单抗奥唑米星化疗的儿童急性髓系白血病患者中的临床意义。
Clin Cancer Res. 2013 Mar 15;19(6):1620-7. doi: 10.1158/1078-0432.CCR-12-3115. Epub 2013 Feb 26.

CD33 splicing SNP regulates expression levels of CD33 in normal regenerating monocytes in AML patients.

作者信息

Lamba Jatinder K, Voigt Andrew P, Chauhan Lata, Shin Miyoung, Aplenc Richard, Eidenschink Brodersen Lisa, Gamis Alan S, Meshinchi Soheil, Loken Michael R

机构信息

a Department of Pharmacotherapy and Translational Research , University of Florida , Gainesville , FL , USA.

b Hematologics Inc , Seattle , WA , USA.

出版信息

Leuk Lymphoma. 2018 Sep;59(9):2250-2253. doi: 10.1080/10428194.2017.1421756. Epub 2018 Jan 10.

DOI:10.1080/10428194.2017.1421756
PMID:29320902
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7199442/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c91c/7199442/8e390719e0c5/nihms-1507160-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c91c/7199442/a9af972d331d/nihms-1507160-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c91c/7199442/8e390719e0c5/nihms-1507160-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c91c/7199442/a9af972d331d/nihms-1507160-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c91c/7199442/8e390719e0c5/nihms-1507160-f0002.jpg