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Osteoarthritis in 2017: Latest advances in the management of knee OA.

作者信息

McAlindon Timothy E, Bannuru Raveendhara R

机构信息

Center for Treatment Comparison and Integrative Analysis (CTCIA), Division of Rheumatology, Tufts Medical Center, 800 Washington Street, Boston, Massachusetts 02111, USA.

出版信息

Nat Rev Rheumatol. 2018 Feb;14(2):73-74. doi: 10.1038/nrrheum.2017.219. Epub 2018 Jan 11.

DOI:10.1038/nrrheum.2017.219
PMID:29323340
Abstract
摘要

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本文引用的文献

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Risk factors for joint replacement in knee osteoarthritis; a 15-year follow-up study.膝关节骨关节炎行关节置换的危险因素；一项15年随访研究。
BMC Musculoskelet Disord. 2017 Dec 4;18(1):510. doi: 10.1186/s12891-017-1871-z.
2
Brief Report: A Phase IIb Trial of a Novel Extended-Release Microsphere Formulation of Triamcinolone Acetonide for Intraarticular Injection in Knee Osteoarthritis.简要报告：曲安奈德新型缓释微球关节内注射治疗膝骨关节炎的 IIb 期临床试验。
Arthritis Rheumatol. 2018 Feb;70(2):204-211. doi: 10.1002/art.40364. Epub 2017 Dec 20.
3
A small-molecule inhibitor of the Wnt pathway (SM04690) as a potential disease modifying agent for the treatment of osteoarthritis of the knee.
骨桥蛋白（OPN）通过促进软骨细胞的合成代谢来缓解骨关节炎的进展。
Genes Dis. 2022 Sep 1;10(4):1714-1725. doi: 10.1016/j.gendis.2022.08.010. eCollection 2023 Jul.
4
Recent Advances in Small Molecule Inhibitors for the Treatment of Osteoarthritis.用于治疗骨关节炎的小分子抑制剂的最新进展
J Clin Med. 2023 Mar 2;12(5):1986. doi: 10.3390/jcm12051986.
5
Randomized controlled trial of aquatic exercise for treatment of knee osteoarthritis in elderly people.老年人膝关节骨关节炎水疗运动治疗的随机对照试验
Interv Med Appl Sci. 2019 Oct 7;11(3):161-167. doi: 10.1556/1646.11.2019.19. eCollection 2020 Sep.
6
Bone-Targeted Nanoparticle Drug Delivery System: An Emerging Strategy for Bone-Related Disease.骨靶向纳米颗粒药物递送系统：一种治疗骨相关疾病的新兴策略
Front Pharmacol. 2022 May 31;13:909408. doi: 10.3389/fphar.2022.909408. eCollection 2022.
7
Root Extract Mediates Anti-Inflammatory Effects in Osteoarthritis Synoviocytes through CB2 Activation.根提取物通过激活CB2介导骨关节炎滑膜细胞的抗炎作用。
Pharmaceuticals (Basel). 2022 Apr 9;15(4):457. doi: 10.3390/ph15040457.
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Exercise to Mend Aged-tissue Crosstalk in Bone Targeting Osteoporosis & Osteoarthritis.运动修复靶向骨质疏松症和骨关节炎的组织老化对话。
Semin Cell Dev Biol. 2022 Mar;123:22-35. doi: 10.1016/j.semcdb.2021.08.011. Epub 2021 Sep 4.
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Sci Rep. 2021 Jun 22;11(1):13032. doi: 10.1038/s41598-021-92474-8.
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Nutrients. 2020 Aug 23;12(9):2545. doi: 10.3390/nu12092545.
一种 Wnt 通路的小分子抑制剂（SM04690）作为一种潜在的疾病修饰剂用于治疗膝关节骨关节炎。
Osteoarthritis Cartilage. 2018 Jan;26(1):18-27. doi: 10.1016/j.joca.2017.08.015. Epub 2017 Sep 6.
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A novel Wnt pathway inhibitor, SM04690, for the treatment of moderate to severe osteoarthritis of the knee: results of a 24-week, randomized, controlled, phase 1 study.一种新型 Wnt 通路抑制剂 SM04690 治疗膝关节中重度骨关节炎的 24 周随机对照 1 期研究结果。
Osteoarthritis Cartilage. 2017 Oct;25(10):1598-1606. doi: 10.1016/j.joca.2017.07.006. Epub 2017 Jul 13.
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JAMA. 2017 May 16;317(19):1967-1975. doi: 10.1001/jama.2017.5283.
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Effectiveness and Implications of Alternative Placebo Treatments: A Systematic Review and Network Meta-analysis of Osteoarthritis Trials.替代安慰剂治疗的效果和意义：骨关节炎试验的系统评价和网络荟萃分析。
Ann Intern Med. 2015 Sep 1;163(5):365-72. doi: 10.7326/M15-0623.
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An intra-articular, extended-release formulation of triamcinolone acetonide prolongs and amplifies analgesic effect in patients with osteoarthritis of the knee: a randomized clinical trial.关节内注射曲安奈德长效制剂可延长并增强膝关节骨关节炎患者的镇痛效果：一项随机临床试验。
J Bone Joint Surg Am. 2015 Jun 3;97(11):877-88. doi: 10.2106/JBJS.N.00918.
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OARSI guidelines for the non-surgical management of knee osteoarthritis.美国骨与软组织放射学会膝关节骨关节炎非手术治疗指南
Osteoarthritis Cartilage. 2014 Mar;22(3):363-88. doi: 10.1016/j.joca.2014.01.003. Epub 2014 Jan 24.
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Rate of cartilage loss at two years predicts subsequent total knee arthroplasty: a prospective study.两年时的软骨流失率可预测后续全膝关节置换术：一项前瞻性研究。
Ann Rheum Dis. 2004 Sep;63(9):1124-7. doi: 10.1136/ard.2004.021253. Epub 2004 Apr 28.