Health Services Research Unit, Department of Community Medicine, University of Tromsø, 9037 Tromsø, Norway.
J Affect Disord. 2018 Mar 15;229:206-212. doi: 10.1016/j.jad.2017.12.051. Epub 2017 Dec 28.
We assessed the mediating role of education in the association between childhood disadvantage and psychological distress in adulthood using longitudinal data collected in three waves, from 1994 to 2008, in the framework of the Tromsø Study (N = 4530), a cohort that is representative of men and women from Tromsø.
Education was measured at a mean age of 54.7 years, and psychological distress in adulthood was measured at a mean age of 61.7 years. Ordinary least square regression analysis was used to assess the associations between childhood disadvantage, education, and psychological distress in adulthood. The indirect effects and the proportion (%) of indirect effects of childhood disadvantage (via education) on psychological distress in adulthood were assessed by mediation analysis.
Childhood disadvantage was associated with lower education and higher psychological distress in adulthood (p < 0.05). Lower education was associated with a higher psychological distress in adulthood (p < 0.05). A minor proportion (7.51%, p < 0.05) of the association between childhood disadvantage and psychological distress in adulthood was mediated by education.
Childhood disadvantages were measured retrospectively.
The association between childhood disadvantage and psychological distress in adulthood is primarily independent of education.
我们使用从 1994 年到 2008 年收集的三个波次的纵向数据，在特罗姆瑟研究（代表特罗姆瑟男女的队列）的框架内，评估了教育在童年逆境与成年期心理困扰之间的关联中的中介作用。
教育在平均年龄为 54.7 岁时进行测量，成年期的心理困扰在平均年龄为 61.7 岁时进行测量。我们采用普通最小二乘回归分析来评估童年逆境、教育与成年期心理困扰之间的关联。通过中介分析评估童年逆境（通过教育）对成年期心理困扰的间接效应和间接效应比例（%）。
童年逆境与较低的教育水平和较高的成年期心理困扰相关（p<0.05）。较低的教育水平与较高的成年期心理困扰相关（p<0.05）。童年逆境与成年期心理困扰之间的关联中，只有一小部分（7.51%，p<0.05）通过教育来介导。
童年逆境是回顾性测量的。
童年逆境与成年期心理困扰之间的关联主要独立于教育。
