Department of Surgical Science, Eye Clinic, University of Cagliari, Cagliari, Italy; and.
Clinica Oculistica, San Giovanni di Dio Hospital, Azienda Ospedaliera Universitaria di Cagliari, Cagliari, Italy.
Retin Cases Brief Rep. 2020 Summer;14(3):278-281. doi: 10.1097/ICB.0000000000000698.
To describe an unusual case of polypoidal choroidal vasculopathy secondary to morning glory syndrome successfully treated with three aflibercept intravitreal injections.
Case report.
A 68-year-old white man presented with a 2-month history of diminished vision of his left eye. Fundus examination showed a morning glory syndrome disk anomaly with some perimacular subretinal hemorrhages and lipid depositions. Fundus autofluorescence, fluorescein and green indocyanine angiography, spectral domain optical coherence tomography, and optical coherence tomography angiography were performed and confirmed the presence of a juxtapapillary polypoidal choroidal vasculopathy with intraretinal and subretinal fluid. Patient underwent 3 monthly intravitreal injections of aflibercept and at 4-month follow-up visit, multimodal imaging findings did not show any kind of neovascular lesion activity.
Polypoidal choroidal vasculopathy can occur in morning glory syndrome and it can be successfully treated with anti-vascular endothelial growth factor intravitreal injections of aflibercept.
描述一例成功用 3 次康柏西普玻璃体腔注射治疗的与牵牛花综合征相关的息肉样脉络膜血管病变的不常见病例。
病例报告。
一名 68 岁白人男性，左眼视力下降 2 个月。眼底检查显示牵牛花综合征伴有一些黄斑区视网膜下出血和脂质沉积。进行了眼底自发荧光、荧光素和吲哚青绿血管造影、谱域光相干断层扫描和光相干断层扫描血管造影，证实存在伴有视网膜内和视网膜下液的近节段息肉样脉络膜血管病变。患者接受了 3 次每月玻璃体腔内注射康柏西普的治疗，在 4 个月的随访时，多模态成像结果未显示任何新生血管病变活动。
息肉样脉络膜血管病变可发生于牵牛花综合征，且可通过玻璃体腔内注射抗血管内皮生长因子的康柏西普成功治疗。
