玻璃体内注射阿柏西普治疗与牵牛星综合征相关的息肉状脉络膜血管病变。

INTRAVITREAL AFLIBERCEPT IN THE TREATMENT OF POLYPOIDAL CHOROIDAL VASCULOPATHY ASSOCIATED WITH MORNING GLORY SYNDROME.

机构信息

Department of Surgical Science, Eye Clinic, University of Cagliari, Cagliari, Italy; and.

Clinica Oculistica, San Giovanni di Dio Hospital, Azienda Ospedaliera Universitaria di Cagliari, Cagliari, Italy.

出版信息

Retin Cases Brief Rep. 2020 Summer;14(3):278-281. doi: 10.1097/ICB.0000000000000698.

DOI:10.1097/ICB.0000000000000698

PMID:29324624

Abstract

PURPOSE

To describe an unusual case of polypoidal choroidal vasculopathy secondary to morning glory syndrome successfully treated with three aflibercept intravitreal injections.

METHODS

Case report.

RESULTS

A 68-year-old white man presented with a 2-month history of diminished vision of his left eye. Fundus examination showed a morning glory syndrome disk anomaly with some perimacular subretinal hemorrhages and lipid depositions. Fundus autofluorescence, fluorescein and green indocyanine angiography, spectral domain optical coherence tomography, and optical coherence tomography angiography were performed and confirmed the presence of a juxtapapillary polypoidal choroidal vasculopathy with intraretinal and subretinal fluid. Patient underwent 3 monthly intravitreal injections of aflibercept and at 4-month follow-up visit, multimodal imaging findings did not show any kind of neovascular lesion activity.

CONCLUSION

Polypoidal choroidal vasculopathy can occur in morning glory syndrome and it can be successfully treated with anti-vascular endothelial growth factor intravitreal injections of aflibercept.

摘要

目的

描述一例成功用 3 次康柏西普玻璃体腔注射治疗的与牵牛花综合征相关的息肉样脉络膜血管病变的不常见病例。

方法

病例报告。

结果

一名 68 岁白人男性，左眼视力下降 2 个月。眼底检查显示牵牛花综合征伴有一些黄斑区视网膜下出血和脂质沉积。进行了眼底自发荧光、荧光素和吲哚青绿血管造影、谱域光相干断层扫描和光相干断层扫描血管造影，证实存在伴有视网膜内和视网膜下液的近节段息肉样脉络膜血管病变。患者接受了 3 次每月玻璃体腔内注射康柏西普的治疗，在 4 个月的随访时，多模态成像结果未显示任何新生血管病变活动。