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20岁男性家族性地中海热患者罕见的脑血管意外表现——病例报告

Very Rare Presentation of Cerebrovascular Accident in 20-Year-Old Man With Familial Mediterranean Fever-Case Report.

作者信息

Aghdashi Miramir, Seidmardani Seyed-Mostafa, Vossoughian Sara, Seyed Mokhtari Seyed Arman

机构信息

Department of Rheumatology, Urmia University of Medical Sciences, Urmia, Iran.

Department of Internal Medicine, Urmia University of Medical Sciences, Urmia, Iran.

出版信息

Clin Med Insights Case Rep. 2018 Jan 3;11:1179547617749208. doi: 10.1177/1179547617749208. eCollection 2018.

Abstract

Familial Mediterranean fever (FMF) is characterized by recurrent episodes of fever accompanied by serosal, synovial, or cutaneous inflammation. The central nervous system (CNS) is rarely involved in FMF. The CNS involvement includes demyelinating lesions, posterior reversible encephalopathy syndrome, pseudotumor cerebri, optic neuritis, and cerebral vasculitis. Here, we present a 20-year-old man, a known case of FMF with abrupt left-sided hemiparesis. Brain magnetic resonance imaging revealed right periventricular infarction. Normal echocardiography ruled out cardioembolism, and thrombophilia workup was negative. Therefore, FMF-induced cerebrovascular accident was considered. Although rare, CNS involvement as a result of FMF disease should also be considered when encountering patients with FMF and CNS manifestations.

摘要

家族性地中海热(FMF)的特征是反复发热,并伴有浆膜、滑膜或皮肤炎症。中枢神经系统(CNS)很少受累于FMF。CNS受累包括脱髓鞘病变、后部可逆性脑病综合征、假性脑瘤、视神经炎和脑血管炎。在此,我们报告一名20岁男性,他是一名已知的FMF患者,突发左侧偏瘫。脑部磁共振成像显示右侧脑室周围梗死。正常的超声心动图排除了心源性栓塞,血栓形成倾向检查结果为阴性。因此,考虑为FMF诱发的脑血管意外。虽然罕见,但在遇到有FMF和CNS表现的患者时,也应考虑FMF疾病导致的CNS受累情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a802/5757431/5d64676b2829/10.1177_1179547617749208-fig1.jpg

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