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眼科医生关于局部麻醉药毒性和静脉注射脂质治疗的知识:问卷调查研究

The Knowledge of Eye Physicians on Local Anesthetic Toxicity and Intravenous Lipid Treatment: Questionnaire Study.

作者信息

Urfalıoğlu Aykut, Urfalıoğlu Selma, Öksüz Gözen

机构信息

Sütçü İmam University Faculty of Medicine, Department of Anesthesiology and Reanimation, Kahramanmaraş, Turkey.

Necip Fazıl State Hospital, Opthalmology Clinic, Kahramanmaraş, Turkey.

出版信息

Turk J Ophthalmol. 2017 Dec;47(6):320-325. doi: 10.4274/tjo.79446. Epub 2017 Dec 25.

Abstract

OBJECTIVES

To evaluate the knowledge of ophthalmologists regarding local anesthesia toxicity syndrome (LATS) and intravenous lipid emulsion used in treatment, and to raise awareness of this issue.

MATERIALS AND METHODS

A questionnaire comprising 14 questions about demographics, local anesthesia (LA) use, toxicity, and treatment methods was administered to ophthalmologists at different hospitals.

RESULTS

The study included 104 ophthalmologists (25% residents, 67.3% specialists, 7.7% faculty members) with a mean age of 35.71±6.53 years. The highest number of participants was from state hospitals (65.4%), and 34.6% of the physicians had been working in ophthalmology for more than 10 years. Seventy-six percent of the participants reported using LA every day or more than twice a week, but 56.7% had received no specific training on this subject. No statistically significant difference was observed between different education levels and the rates of training (p=0.419). Bupivacaine was the most preferred LA and the majority of respondents (97.1%) did not use a test dose. Allergy (76%) and hypotension (68.3%) were the most common responses for early findings of LATS, while cardiac arrest (57.4%) and hepatotoxicity (56.4%) were given for late findings. The most common responses concerning the prevention of LATS included monitorization (72.4%) and use of appropriate doses (58.2%). Symptomatic treatment was selected by 72.4% of respondents and cardiopulmonary resuscitation and antihistamine treatment by 58.8%. Of the ophthalmologists in the study, 62.5% had never encountered LATS. The use of 20% intravenous lipid emulsion therapy for toxicity was known by 65% of the physicians, but only 1 participant stated having used it previously.

CONCLUSION

The importance of using 20% lipid emulsion in LATS treatment and having it available where LA is administered must be emphasized, and there should be compulsory training programs for ophthalmologists on this subject.

摘要

目的

评估眼科医生对局部麻醉中毒综合征(LATS)及用于治疗的静脉注射脂质乳剂的了解情况,并提高对此问题的认识。

材料与方法

向不同医院的眼科医生发放一份包含14个问题的问卷,内容涉及人口统计学、局部麻醉(LA)的使用、毒性及治疗方法。

结果

该研究纳入了104名眼科医生(25%为住院医师,67.3%为专科医生,7.7%为教员),平均年龄为35.71±6.53岁。参与人数最多的来自公立医院(65.4%),34.6%的医生从事眼科工作超过10年。76%的参与者报告每天或每周使用LA超过两次,但56.7%的人未接受过关于该主题的特定培训。不同教育水平与培训率之间未观察到统计学上的显著差异(p = 0.419)。布比卡因是最常用的LA,大多数受访者(97.1%)未使用试验剂量。过敏(76%)和低血压(68.3%)是LATS早期发现的最常见反应,而心脏骤停(57.4%)和肝毒性(56.4%)是晚期发现的最常见反应。关于预防LATS的最常见反应包括监测(72.4%)和使用适当剂量(58.2%)。72.4%的受访者选择对症治疗,58.8%的受访者选择心肺复苏和抗组胺治疗。在该研究的眼科医生中,62.5%从未遇到过LATS。65%的医生知道使用20%静脉注射脂质乳剂治疗毒性,但只有1名参与者表示之前使用过。

结论

必须强调在LATS治疗中使用20%脂质乳剂并在实施LA的地方备有该药物的重要性,并且应该为眼科医生制定关于该主题的强制性培训计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2d4a/5758766/3cd5a37ed7ba/TJO-47-320-g3.jpg

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