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球后麻醉后出现全身性癫痫发作和短暂性对侧偏瘫:一例报告

Generalized seizures and transient contralateral hemiparesis following retrobulbar anesthesia: a case report.

作者信息

Dettoraki Maria, Dimitropoulou Chrisafoula, Nomikarios Nikolaos, Moschos Marilita M, Brοuzas Dimitrios

机构信息

1st Department of Ophthalmology, University of Athens, "G. Gennimatas" General Hospital of Athens, 10 G. Papandreou Str, Byron, Athens, 16231, Greece.

Department of Anesthesiology, "G. Gennimatas" General Hospital of Athens, Athens, Greece.

出版信息

BMC Anesthesiol. 2015 Jul 28;15:108. doi: 10.1186/s12871-015-0084-y.

DOI:10.1186/s12871-015-0084-y
PMID:26215739
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4517554/
Abstract

BACKGROUND

Retrobulbar block is a local anesthetic technique widely used for intraocular surgery. Although retrobulbar anesthesia is considered to be relatively safe, a number of serious adverse events have been reported. To our knowledge, immediate onset of generalized seizures with contralateral hemiparesis after retrobulbar anesthesia has not been reported.

CASE PRESENTATION

A 62-year-old Caucasian healthy male with a right eye retinal detachment was admitted for pars plana vitrectomy. During retrobulbar anesthesia with ropivacaine and before needle withdrawal, the patient developed twitching of the face which rapidly progressed to generalized tonic-clonic seizures. Arterial oxygen saturation decreased to 75 %. Chin lift was performed and 100 % oxygen was administrated via face mask, which increased saturation to 99 %. Midazolam 2 mg was administrated intravenously to control seizures. After cessation of seizures, left-sided hemiparesis was evident. Brain computed tomography and electroencephalogram were normal 3 h later. The patient underwent pars plana vitrectomy under general anesthesia 4 days later.

CONCLUSION

Serious complications of local anesthesia for ophthalmic surgery are uncommon. We present a case in which generalized tonic-clonic seizures developed during retrobulbar anesthesia, followed by transient contralateral hemiparesis. The early onset of seizures indicated intra-arterial injection of the anesthetic. Our case suggested the need for close monitoring during the performance of retrobulbar anesthesia and the presence of well-trained personnel for early recognition and immediate management of the complications.

摘要

背景

球后阻滞是一种广泛用于眼科手术的局部麻醉技术。尽管球后麻醉被认为相对安全,但仍有一些严重不良事件的报道。据我们所知,球后麻醉后立即出现全身性癫痫发作并伴有对侧偏瘫的情况尚未见报道。

病例报告

一名62岁的白种健康男性因右眼视网膜脱离入院接受玻璃体切除术。在使用罗哌卡因进行球后麻醉过程中,拔针前患者出现面部抽搐,迅速发展为全身性强直阵挛性癫痫发作。动脉血氧饱和度降至75%。进行了抬颏操作,并通过面罩给予100%氧气,使饱和度升至99%。静脉注射2mg咪达唑仑以控制癫痫发作。癫痫发作停止后,左侧偏瘫明显。3小时后脑部计算机断层扫描和脑电图检查正常。4天后患者在全身麻醉下接受了玻璃体切除术。

结论

眼科手术局部麻醉的严重并发症并不常见。我们报告了一例在球后麻醉期间发生全身性强直阵挛性癫痫发作,随后出现短暂性对侧偏瘫的病例。癫痫发作的早期发生提示麻醉剂动脉内注射。我们的病例表明在进行球后麻醉时需要密切监测,并配备训练有素的人员以便早期识别和立即处理并发症。

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本文引用的文献

1
Convulsions during cataract surgery under peribulbar anesthesia: a case report.球周麻醉下白内障手术期间的惊厥:一例报告
J Med Case Rep. 2014 Jun 23;8:218. doi: 10.1186/1752-1947-8-218.
2
Delayed convulsions and brief contralateral hemiparesis after retrobulbar block.球后阻滞术后迟发性惊厥和短暂性对侧偏瘫。
Reg Anesth Pain Med. 2006 May-Jun;31(3):275-8. doi: 10.1016/j.rapm.2006.01.004.
3
Apnea and seizures following retrobulbar local anesthetic injection.球后局部麻醉注射后出现呼吸暂停和癫痫发作。
J Clin Anesth. 2003 Jun;15(4):267-70. doi: 10.1016/s0952-8180(03)00025-4.
4
The National Survey of Local Anaesthesia for Ocular Surgery. II. Safety profiles of local anaesthesia techniques.眼部手术局部麻醉全国调查。II. 局部麻醉技术的安全性概况。
Eye (Lond). 1999 Apr;13 ( Pt 2):196-204. doi: 10.1038/eye.1999.50.
5
Ropivacaine for peribulbar anesthesia.用于球周麻醉的罗哌卡因。
Reg Anesth Pain Med. 1999 Jul-Aug;24(4):337-40. doi: 10.1016/s1098-7339(99)90108-6.
6
Medical causes of seizures.
Lancet. 1998 Aug 1;352(9125):383-90. doi: 10.1016/S0140-6736(98)02158-8.
7
Adverse effects and drug interactions associated with local and regional anaesthesia.与局部和区域麻醉相关的不良反应及药物相互作用。
Drug Saf. 1998 Apr;18(4):221-50. doi: 10.2165/00002018-199818040-00001.
8
Central nervous and cardiovascular effects of i.v. infusions of ropivacaine, bupivacaine and placebo in volunteers.静脉输注罗哌卡因、布比卡因和安慰剂对志愿者中枢神经系统和心血管系统的影响。
Br J Anaesth. 1997 May;78(5):507-14. doi: 10.1093/bja/78.5.507.
9
Complications of local anaesthesia for ophthalmic surgery.
Br J Anaesth. 1995 Jul;75(1):93-6. doi: 10.1093/bja/75.1.93.
10
Cardiopulmonary arrest after retrobular block.
Am J Ophthalmol. 1980 Sep;90(3):425-7. doi: 10.1016/s0002-9394(14)74932-3.