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免疫功能正常成年人中的胃血管侵袭性毛霉病,一种罕见病例。

Gastric Angioinvasive Mucormycosis in Immunocompetent Adult, A Rare Occurrence.

作者信息

Nasa Mukesh, Sharma Zubin, Lipi Lipika, Sud Randhir

机构信息

Consultant.

Gastroenetrology Fellow.

出版信息

J Assoc Physicians India. 2017 Dec;65(12):103-104.

Abstract

Mucormycosis is a rare, opportunistic fungal infection that occurs almost exclusively in immunocompromised hosts such as patients with diabetes mellitus, leukemia, lymphoma, renal disease, septicemia, burns, malnutrition, and following long-term treatment with steroids and antibiotics. Based on the clinical presentation and involvement, mucormycosis is classified as six major forms, namely, rhinocerebral, pulmonary, cutaneous, gastrointestinal (GI), disseminated and miscellaneous, with rhinocerebral and pulmonary being the common forms. GI mucormycosis is rare, accounting for only 7% of all cases; however, the mortality rate is as high as 85%. Here we report a case of a young immunocompetent male who developed gastric invasive mucormycosis during an acute illness and succumbed to it despite all supportive care.

摘要

毛霉病是一种罕见的机会性真菌感染,几乎仅发生于免疫功能低下的宿主,如糖尿病、白血病、淋巴瘤、肾病、败血症、烧伤、营养不良患者,以及长期接受类固醇和抗生素治疗的患者。根据临床表现和受累部位,毛霉病分为六种主要类型,即鼻脑型、肺型、皮肤型、胃肠道型、播散型和其他型,其中鼻脑型和肺型最为常见。胃肠道毛霉病较为罕见,仅占所有病例的7%;然而,其死亡率高达85%。在此,我们报告一例年轻的免疫功能正常男性,在急性疾病期间发生胃侵袭性毛霉病,尽管给予了所有支持治疗,仍最终死亡。

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