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[原发性皮肤毛霉病:两例报告及文献复习]

[Primary cutaneous mucormycosis: two case reports and review of the literature].

作者信息

Tapia E Oscar, Chahín A Carolina, Concha F Carla

机构信息

Departamento de Anatomía Patológica, Facultad de Medicina, Universidad de La Frontera, Temuco, Chile.

出版信息

Rev Chilena Infectol. 2011 Jun;28(3):269-73. Epub 2011 Jul 14.

Abstract

Mucormycosis or zygomycosis is a rare opportunistic infection caused by aerobic saprophytic fungus that belongs to the class of Zygomycetes Mucorales family. These organisms live in the environment and enter the body by air, gastrointestinal or skin routes, through solutions of continuity of the skin. This microorganism is generally not pathogenic for immunocompetent hosts, being the development of the disease linked with the immune status of the subject. Its mortality is around 50-60%; sometimes in spite of early diagnosis and treatment initiation it has a fatal course. Six clinical forms of mucormycosis are described: rhinocerebral, cutaneous, pulmonary, disseminated, gastrointestinal and miscellaneous form. Two cases of patients with primary cutaneous mucormycosis diagnosed in the Pathology Unit of Hernan Henriquez Aravena Hospital of Temuco, Chile are presented here.

摘要

毛霉病或接合菌病是一种由需氧腐生真菌引起的罕见机会性感染,该真菌属于接合菌纲毛霉目家族。这些生物体生活在环境中,通过空气、胃肠道或皮肤途径,经皮肤连续性破损处进入人体。这种微生物通常对免疫功能正常的宿主不致病,疾病的发生与个体的免疫状态有关。其死亡率约为50%-60%;有时尽管早期诊断并开始治疗,病情仍会发展至致命。毛霉病有六种临床类型:鼻脑型、皮肤型、肺型、播散型、胃肠型和其他类型。本文介绍了在智利特木科市埃尔南·恩里克·阿拉韦纳医院病理科诊断出的两例原发性皮肤毛霉病患者的病例。

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