Nowosielska-Grygiel Joanna, Pietkiewicz Piotr, Owczarek Kalina, Olszewski Jurek, Miłoński Jarosław
Department of Otolaryngology, Oncological laryngology, Audiology, and Phoniatrics, II Chair of Otolaryngology, Medical University, Lodz, Poland.
Otolaryngol Pol. 2017 Dec 30;71(6):27-32. doi: 10.5604/01.3001.0010.7195.
The aim of this study was to analyse the occurrence of inverted papillomas of the nose and paranasal sinuses in patients that underwent endoscopic sinus surgery in our department.
Between 2006 and 2016, 3,574 patients underwent surgery due to paranasal sinus diseases. Patients were qualified for surgery based on medical history, computed tomography, and laboratory tests. Data were gathered from medical files, and they included age, sex, and histopathological diagnosis.
Among 3,574 patients that underwent surgery due to chronic inflammatory changes, on histopathology, inverted papillomas were diagnosed in 80 patients, including 31 women (38.75%) and 49 men (61.25%). Most patients were aged 60-70 years (women, 12.5%; men, 15%) or 50-60 years (women, 5%; men, 21.25%). Between 2006 and 2016, the number of surgeries ranged from 264 (7.38%) in 2013 to 355 (9.93%) in 2016, and the number of inverted papillomas ranged from 4 in 2007 and 2015 (1.23%) to 12 in 2014 (3.87%). Over the last 4 years of the study period, the incidence of inverted papillomas increased.
Among 3,574 patients operated on due to chronic inflammatory changes, on histopathology, inverted papillomas were diagnosed in 80 cases (2.23%); thus, all patients qualified for endoscopic surgery due to inflammatory or hypertrophic changes should undergo rhino-fiberoscopy. Recurrence of inverted papillomas was observed in 17.50%, typically in patients with nasal polyps that co-occurred with inverted papillomas. We regard rhino-fiberoscopy as the most valuable method for detecting tumour recurrence in patients after surgery for inverted papillomas.
本研究的目的是分析在我院接受鼻内镜鼻窦手术的患者中鼻及鼻窦内翻性乳头状瘤的发病情况。
2006年至2016年间，3574例患者因鼻窦疾病接受手术。根据病史、计算机断层扫描和实验室检查确定患者是否适合手术。数据从病历中收集，包括年龄、性别和组织病理学诊断。
在3574例因慢性炎症性改变接受手术的患者中，经组织病理学检查，80例诊断为内翻性乳头状瘤，其中女性31例（38.75%），男性49例（61.25%）。大多数患者年龄在60 - 70岁（女性，12.5%；男性，15%）或50 - 60岁（女性，5%；男性，21.25%）。2006年至2016年间，手术例数从2013年的264例（7.38%）到2016年的355例（9.93%）不等，内翻性乳头状瘤例数从2007年和2015年的4例（1.23%）到2014年的12例（3.87%）不等。在研究期的最后4年，内翻性乳头状瘤的发病率有所上升。
在3574例因慢性炎症性改变接受手术的患者中，经组织病理学检查，80例（2.23%）诊断为内翻性乳头状瘤；因此，所有因炎症或肥厚性改变而适合接受内镜手术的患者均应接受鼻纤维镜检查。内翻性乳头状瘤的复发率为17.50%，通常发生在伴有内翻性乳头状瘤的鼻息肉患者中。我们认为鼻纤维镜检查是检测内翻性乳头状瘤患者术后肿瘤复发最有价值的方法。
