自身免疫性水疱病中的指甲改变：一项病例对照研究。
Nail changes in autoimmune blistering disorders: A case-control study.
作者信息
Gopal Vaishnavi, Shenoy Manjunath Mala, Bejai Vishal, Nargis Thansiha
机构信息
Department of Dermatology, Venereology and Leprosy, Yenepoya Medical College, Yenepoya University, Mangalore, Karnataka, India.
出版信息
Indian J Dermatol Venereol Leprol. 2018 May-Jun;84(3):373. doi: 10.4103/ijdvl.IJDVL_19_17.
BACKGROUND
Pemphigus and pemphigoid disorders produce blistering cutaneous lesions. Earlier case reports state that nail involvement is uncommon in these autoimmune blistering disorders.
AIMS AND OBJECTIVES
To study nail changes in autoimmune blistering disorders.
METHODS
A case-control study was conducted where 40 cases and 40 controls were evaluated for nail changes.
RESULTS
Nail changes were seen in 72.5% of cases and 17.5% of controls. The most common nail findings were paronychia and onychorrhexis.
LIMITATIONS
Small sample size; short study duration; nail biopsy could not be done.
CONCLUSION
Our findings indicate that the inflammatory nature of the blistering cutaneous disease is often reflected conspicuously in the nails.
背景
天疱疮和类天疱疮疾病会产生皮肤水疱性病变。早期病例报告称，在这些自身免疫性水疱性疾病中，指甲受累并不常见。
目的
研究自身免疫性水疱性疾病中的指甲变化。
方法
进行了一项病例对照研究，对40例病例和40例对照进行了指甲变化评估。
结果
72.5%的病例和17.5%的对照出现了指甲变化。最常见的指甲表现是甲沟炎和甲纵裂。
局限性
样本量小；研究持续时间短；无法进行指甲活检。
结论
我们的研究结果表明，皮肤水疱性疾病的炎症性质通常在指甲上有明显体现。
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