Li Qifeng, Ma Xiangyun, Wang Huijie, Wang Yang, Zheng Xinwei, Chen Da
Opt Express. 2018 Jan 8;26(1):525-530. doi: 10.1364/OE.26.000525.
Raman spectral imaging has been widely used as a very important analytical tool in various fields. For obtaining the high spectral signal-to-noise ratio Raman images, the long integration time is necessary, which is placing a limit on the application of Raman spectral imaging. We introduce a simple and feasible numerical method of the Three-dimensional Low Rank Estimation (3D-LRE), which can speed up the data acquisition process of the Raman spectral imaging. The spectral signal-to-noise ratio of the Raman images can be increased by over 75 times and the speed of the data acquisition can be improved by over 30 times. By combining with line-scan or multifocus-scan techniques, the Raman images can be obtained in a few seconds.
拉曼光谱成像作为一种非常重要的分析工具，已在各个领域得到广泛应用。为了获得高光谱信噪比的拉曼图像，需要较长的积分时间，这限制了拉曼光谱成像的应用。我们介绍一种简单可行的三维低秩估计（3D-LRE）数值方法，它可以加快拉曼光谱成像的数据采集过程。拉曼图像的光谱信噪比可提高75倍以上，数据采集速度可提高30倍以上。通过与线扫描或多焦点扫描技术相结合，几秒钟内即可获得拉曼图像。
