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[苏联东北部当地居民群体的遗传结构。五、楚科奇埃文人]

[Genetic structure of the populations of native inhabitants in the northeastern USSR. V. The Chukot Evens].

作者信息

Solovenchuk L L, Glushenko A N

出版信息

Genetika. 1985 Sep;21(9):1557-66.

PMID:2933299
Abstract

The genetic structure of two Chukot Evens subpopulations (314 individuals) for electrophoretic protein systems and taste sensitivity to PTC was studied. 17 of the 39 loci were polymorphic (43.59%). The following systems were completely monomorphic: diaphorase NAD H (Dia); glucose-6-phosphate dehydrogenase (G-6-PD); glutamatoxalate transaminase (GOT); carbonic anhydrase (Ca-1); catalase (Ct), lactate dehydrogenase (loci LDH-A and LDH-B); leucine aminopeptidase (Lap); malate dehydrogenase (MDH); purine nucleoside phosphorylase (PNP); superoxide phosphorylase (PNP); superoxide dismutase (SOD); phosphoglucomutase-2 (PGM2); cholinesterase (locus E1); red cell esterase (4 loci); albumin (Alb); hemoglobin (Hb A and B); ceruloplasmin (Cp); and blood, gren, using the standard method. The following systems were polymorphic: red cell acid phosphatase (AcP); phosphoglucomutase-1 (PGM1); 6-phosphogluconate dehydrogenase (PGD); glutamatepyruvate transaminase (GPT); glyoxalase-1 (GLO-1); esterase (EsD); adenilatkinase (AK); alkaline phosphatase (Pp); cholinesterase (locus E2); haptoglobin (Hp); transferrin (Tf); group-specific component (Gc) and ABO, MN, Lewis, P blood groups and taste sensitivity to PTC. The following allele frequencies for polymorphic loci have been detected: AKI = 0.994; GLO = 1I = 0.082; GPT1 = 0.653; AcPA = 0.400; AcPB = 0.599; AcPC = 0.001; PGDA = 0.944; PGM1(1) = 0.906; EsD1 = 0.897; E2+ = 0.048; HpI = 0.394; GcI = 0,919; Tfc = 0.987; r(O) = 0.669; p(A) = 0.184; q(B) = 0.146; M = 0.711; Le = 0.411; P1+ = 0.521; t = 0.295. The genetic structure of Chukot Evens population is significantly nearer to that of the other ethnic groups of the North-East, in comparison with the genetic structure of Evenks of the Middle Siberia.

摘要

对楚科奇埃文人的两个亚群体(314人)的电泳蛋白质系统和对苯硫脲(PTC)的味觉敏感性的遗传结构进行了研究。39个基因座中有17个是多态性的(43.59%)。以下系统完全是单态性的:NADH黄递酶(Dia);葡萄糖-6-磷酸脱氢酶(G-6-PD);谷氨酸草酰乙酸转氨酶(GOT);碳酸酐酶(Ca-1);过氧化氢酶(Ct),乳酸脱氢酶(基因座LDH-A和LDH-B);亮氨酸氨肽酶(Lap);苹果酸脱氢酶(MDH);嘌呤核苷磷酸化酶(PNP);超氧化物磷酸化酶(PNP);超氧化物歧化酶(SOD);磷酸葡萄糖变位酶-2(PGM2);胆碱酯酶(基因座E1);红细胞酯酶(4个基因座);白蛋白(Alb);血红蛋白(Hb A和B);铜蓝蛋白(Cp);以及血液、绿色,采用标准方法。以下系统是多态性的:红细胞酸性磷酸酶(AcP);磷酸葡萄糖变位酶-1(PGM1);6-磷酸葡萄糖酸脱氢酶(PGD);谷氨酸丙酮酸转氨酶(GPT);乙二醛酶-1(GLO-1);酯酶(EsD);腺苷酸激酶(AK);碱性磷酸酶(Pp);胆碱酯酶(基因座E2);触珠蛋白(Hp);转铁蛋白(Tf);组特异性成分(Gc)以及ABO、MN、Lewis、P血型和对PTC的味觉敏感性。已检测到多态性基因座的以下等位基因频率:AKI = 0.994;GLO = 1I = 0.082;GPT1 = 0.653;AcPA = 0.400;AcPB = 0.599;AcPC = 0.001;PGDA = 0.944;PGM1(1) = 0.906;EsD1 = 0.897;E2+ = 0.048;HpI = 0.394;GcI = 0,919;Tfc = 0.987;r(O) = 0.669;p(A) = 0.184;q(B) = 0.146;M = 0.711;Le = 0.411;P1+ = 0.521;t = 0.295。与西伯利亚中部埃文基人的遗传结构相比,楚科奇埃文人的遗传结构明显更接近东北其他民族的遗传结构。

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