a Department of Ophthalmology , Sapienza University of Rome , Rome , Italy.
Ocul Immunol Inflamm. 2019;27(3):435-446. doi: 10.1080/09273948.2017.1416149. Epub 2018 Jan 15.
: To study epidemiology and clinical findings of cataract in HIV+ patients. : A total of 32 HIV+ patients, 11 with uveitis/retinitis before surgery and 21 without, mean follow-up 44.9 ± 36.6 months, and 114 HIV- patients, 57 with uveitis/retinitis before surgery and 57 without, were retrospectively compared. : Visual acuity improved in all HIV+ patients ( < 0.001), who were younger ( = 0.01) and more frequently males ( = 0.027). HIV+ patients with uveitis prior surgery improved less ( = 0.046) than HIV- ( < 0.001); their anterior chamber inflammation was similar to baseline. Male sex ( = 0.005), younger age ( < 0.001), dyslipidaemia ( = 0.058), HBV+ ( = 0.037), and unilateral cataract ( = 0.001) were more frequent in HIV+ patients with senile cataract, but they showed the same postoperative course as HIV- patients. : Cataract surgery in HIV+ patients is safe and effective. Uveitis prior to surgery did not significantly affect the postoperative course. Systemic comorbidities are more frequent in HIV+ patients with senile cataract than in HIV- subjects.
: 研究 HIV 阳性患者白内障的流行病学和临床发现。 : 共纳入 32 例 HIV 阳性患者，11 例术前有葡萄膜炎/视网膜炎，21 例无，平均随访 44.9±36.6 个月；并回顾性比较了 114 例 HIV 阴性患者，57 例术前有葡萄膜炎/视网膜炎，57 例无。 : 所有 HIV 阳性患者的视力均有所改善（P<0.001），且这些患者更年轻（P=0.01），男性更多（P=0.027）。与 HIV 阴性患者相比（P<0.001），术前有葡萄膜炎的 HIV 阳性患者视力改善较少（P=0.046）；其前房炎症与基线相似。与 HIV 阴性患者相比，男性（P=0.005）、年龄较小（P<0.001）、血脂异常（P=0.058）、HBV+（P=0.037）和单侧白内障（P=0.001）在 HIV 阳性老年性白内障患者中更为常见，但他们的术后过程与 HIV 阴性患者相同。 : HIV 阳性患者白内障手术安全有效。术前葡萄膜炎对术后病程无显著影响。与 HIV 阴性患者相比，老年性白内障的 HIV 阳性患者更常合并全身性疾病。
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