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预测香港青少年可能出现的抑郁缓解的因素——一项大规模的纵向研究。

Predictors of remission from probable depression among Hong Kong adolescents - A large-scale longitudinal study.

机构信息

Centre for Health Behaviours Research, JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China; The Chinese University of Hong Kong Shenzhen Research Institute, Shenzhen, China.

Centre for Health Behaviours Research, JC School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China; The Chinese University of Hong Kong Shenzhen Research Institute, Shenzhen, China.

出版信息

J Affect Disord. 2018 Mar 15;229:491-497. doi: 10.1016/j.jad.2017.12.080. Epub 2018 Jan 2.

Abstract

BACKGROUND

This study investigated the incidence of remission from probable depression among adolescents in Hong Kong. Remissions were defined as having Center for Epidemiological Studies Depression Scale (CESD) scores changed from ≥16 at baseline to <16 over the 12-month follow-up period. The study tested the predictors of remissions, including perceived changes in family support, self-efficacy, self-esteem, positive affect, negative events, social anxiety, and loneliness.

METHODS

The study surveyed 9666 secondary school students and identified 5487 (57%) students with probable depression in Hong Kong. A questionnaire assessing the levels of the aforementioned variables was completed at baseline and at the 12-month follow-up.

RESULTS

Among participants with probable depression at baseline, 23.2% remitted from depression at follow-up. Remissions were more common among males than females. Univariate logistic regression showed that perceived changes in all the aforementioned variables significantly predicted remission for both males and females. The same is true for most of these variables when they were entered together into multiple logistic regression models (with and without controlling for baseline CESD scores), except for family support in the female model and self-efficacy in both male and female models.

LIMITATIONS

Limitations include potential self-report bias and only one follow-up observation over time. The design treats cases of probable mild to severe depression as a single group (CESD≥16).

CONCLUSIONS

The findings are potentially useful for designing and guiding related intervention programs. Results highlight the importance of long-term follow-up of those screened as probable depression to understand the course of changes in levels of depression.

摘要

背景

本研究调查了香港青少年中可能患有抑郁症的患者的缓解率。缓解定义为在 12 个月的随访期间,从基线时中心流行病学研究抑郁量表(CESD)得分≥16 降至<16。该研究检验了缓解的预测因素,包括感知到的家庭支持、自我效能、自尊、积极情绪、消极事件、社交焦虑和孤独感的变化。

方法

该研究调查了 9666 名中学生,在香港确定了 5487 名(57%)患有可能患有抑郁症的学生。基线和 12 个月随访时,使用评估上述变量水平的问卷进行评估。

结果

在基线时患有可能患有抑郁症的参与者中,有 23.2%在随访时缓解了抑郁症。男性缓解的比例高于女性。单变量逻辑回归显示,所有上述变量的感知变化均显著预测了男性和女性的缓解。当将这些变量同时纳入多变量逻辑回归模型(包括和不包括基线 CESD 评分)时,除了女性模型中的家庭支持和男性和女性模型中的自我效能外,对于大多数变量都是如此。

局限性

限制包括潜在的自我报告偏倚和仅随时间进行一次随访观察。该设计将可能患有轻度至重度抑郁症的病例视为一个单一的组(CESD≥16)。

结论

这些发现对于设计和指导相关干预计划可能具有一定的作用。结果强调了对那些筛查为可能患有抑郁症的患者进行长期随访的重要性,以了解抑郁水平变化的过程。

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