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[甲状腺疾病的硒治疗]

[Selenium treatment in thyreopathies].

作者信息

Sotak Štefan

出版信息

Vnitr Lek. 2018 Winter;63(12):949-951.

Abstract

Selenium (latin Selenium) is a micronutrient embedded in several proteins. In adults, the thyroid is the organ with the highest amount of selenium per gram of tissue. Selenium levels in the body depend on the characteristics of the population and its diet and geographic area. In the thyroid, selenium is required for the antioxidant function and for the metabolism of thyroid hormones. The literature suggests that selenium supplementation of patients with Hashimotos thyroiditis is associated with a reduction in antithyroperoxidase antibody levels. Selenium supplementation also in mild Graves orbitopathy is associated with delayed progression of ocular disorders. As a consequence of this observation The European Group on Graves Orbitopathy recommend six months selenium preparates supportive therapy for patients with mild form of Graves orbitopathy.Key words: Graves-Basedows disease - Hashimotos thyroiditis - selenium - supplementation.

摘要

硒(拉丁文:Selenium)是一种存在于多种蛋白质中的微量营养素。在成年人中,甲状腺是每克组织中含硒量最高的器官。体内的硒水平取决于人群的特征、饮食和地理区域。在甲状腺中,硒对于抗氧化功能以及甲状腺激素的代谢是必需的。文献表明,补充硒与桥本甲状腺炎患者抗甲状腺过氧化物酶抗体水平的降低有关。补充硒对轻度格雷夫斯眼眶病也有作用,可延缓眼部疾病的进展。基于这一观察结果,欧洲格雷夫斯眼眶病研究小组建议对轻度格雷夫斯眼眶病患者进行为期六个月的硒制剂支持治疗。关键词:格雷夫斯-巴塞多氏病 - 桥本甲状腺炎 - 硒 - 补充

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