Goraya Jatinder Singh, Berry Shivankshi, Saggar Kavita, Ahluwalia Archana
1 Department of Pediatrics, Division of Pediatric Neurology, Ludhiana, Punjab, India.
2 Department of Radiodiagnosis, Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
J Child Neurol. 2018 Feb;33(2):146-152. doi: 10.1177/0883073817750501.
The authors retrospectively reviewed charts of the children with basal ganglia stroke who either had preceding minor head injury or showed basal ganglia calcification on computed tomography (CT) scan. Twenty children, 14 boys and 6 girls were identified. Eighteen were aged between 7 months to 17 months. Presentation was with hemiparesis in 17 and seizures in 3. Preceding minor head trauma was noted in 18. Family history was positive in 1 case. Bilateral basal ganglia calcification on CT scan was noted in 18. Brain magnetic resonance imaging done in 18 infants showed acute or chronic infarcts in basal ganglia. Results of other laboratory and radiological investigations were normal. Four infants were lost to follow-up, 9 achieved complete or nearly completely recovery, and 7 had persistent neurological deficits. Basal ganglia calcification likely represents mineralized lenticulostriate arteries, a marker of lenticulostriate vasculopathy. Abnormal lenticulostriate vessels are vulnerable to injury and thrombosis after minor head trauma resulting in stroke.
作者回顾性分析了基底节区卒中患儿的病历，这些患儿要么之前有轻度头部损伤，要么在计算机断层扫描（CT）上显示基底节区钙化。共确定了20名儿童，其中14名男孩和6名女孩。18名年龄在7个月至17个月之间。表现为偏瘫的有17例，癫痫发作的有3例。18例有轻度头部外伤史。家族史阳性1例。CT扫描显示18例双侧基底节区钙化。18名婴儿进行的脑磁共振成像显示基底节区有急性或慢性梗死。其他实验室和影像学检查结果均正常。4名婴儿失访，9名完全或几乎完全康复，7名有持续性神经功能缺损。基底节区钙化可能代表矿化的豆纹动脉，是豆纹动脉病的一个标志。异常的豆纹血管在轻度头部外伤后易受损伤和血栓形成，从而导致卒中。
