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化脓性肝脓肿通过横膈膜延伸导致的心包炎和脓胸一例罕见病例。

A rare case of pericarditis and pleural empyema secondary to transdiaphragmatic extension of pyogenic liver abscess.

机构信息

Department of Internal Medicine, Chonnam National University Hospital, Gwangju, South Korea.

Department of Radiology, Chonnam National University Hospital, Gwangju, South Korea.

出版信息

BMC Infect Dis. 2018 Jan 15;18(1):40. doi: 10.1186/s12879-018-2953-8.

Abstract

BACKGROUND

Transdiaphragmatic extension of pyogenic liver abscess is the rarest cause of pericarditis and pleural empyema. It is a rapidly progressive and highly lethal infection with mortality rates reaching 100% if left untreated. However, the transmission route, treatment methods and prognosis have not been well studied.

CASE PRESENTATION

A 65-year-old male patient presented with a fever, dyspnea, and right upper quadrant abdominal pain. Computed tomography of the chest and abdomen showed huge liver abscess without full liquefaction in the left lobe, large amount of left pleural effusion, and mild pericardial effusion, and the patient was treated with parenteral antibiotics and pigtail insertion at the left pleura. However, four days later, cardiac tamponade was developed and surgical drainage of the abscess and pericardium was performed. Klebsiella pneumonia was isolated from pleural empyema. Twenty-five days after surgery, the patient was discharged without any complications.

CONCLUSIONS

Herein, we report a rare case of pleural empyema and pericarditis in that resulted from the extension of huge pyogenic liver abscess. Early surgical treatment may have prevented progression of the pericarditis to the more dismal purulent pericarditis. We also review pertinent English literature on pericarditis as a complication of PLA.

摘要

背景

化脓性肝脓肿经横膈延伸是心包炎和脓胸的最罕见病因。这是一种快速进展且高度致命的感染,如果不治疗,死亡率高达 100%。然而,其传播途径、治疗方法和预后尚未得到充分研究。

病例介绍

一名 65 岁男性患者出现发热、呼吸困难和右上腹疼痛。胸部和腹部的计算机断层扫描显示左叶巨大肝脓肿未完全液化,大量左侧胸腔积液和轻度心包积液,患者接受了静脉内抗生素和左侧胸腔置管引流治疗。然而,四天后出现心脏压塞,行脓肿和心包切开引流术。从脓胸分离出肺炎克雷伯菌。术后 25 天,患者无任何并发症出院。

结论

本研究报告了一例罕见的巨大化脓性肝脓肿延伸导致脓胸和心包炎的病例。早期手术治疗可能防止了心包炎进展为更严重的化脓性心包炎。我们还回顾了有关 PLA 作为心包炎并发症的相关英文文献。

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