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[无需化疗和输血成功治疗急性早幼粒细胞白血病]

[Successful treatment of acute promyelocytic leukaemia without chemotherapy and blood transfusion].

作者信息

Tøstesen Michael, Østgård Lene S G, Kjeldsen Eigil, Stentoft Jesper, Nørgaard Jan M

出版信息

Ugeskr Laeger. 2018 Jan 15;180(3).

PMID:29336300
Abstract

Untreated acute promyelocytic leukaemia (APL) is a rapidly lethal blood cancer. Conventional treatment consists of all-trans retinoic acid and chemotherapy. Standard chemo-therapy-containing treatments necessitate the use of blood products. This is a case report of typical APL in a 32-year-old female patient, who due to religious conviction refused supportive therapy with blood products. A treatment regimen consisting of all-trans retinoic acid and arsenic trioxide was successful without the use of blood transfusions.

摘要

未经治疗的急性早幼粒细胞白血病(APL)是一种迅速致死的血液癌症。传统治疗包括全反式维甲酸和化疗。含标准化疗的治疗方案需要使用血液制品。本文报告了一名32岁女性典型APL患者的病例,该患者因宗教信仰拒绝接受血液制品支持治疗。由全反式维甲酸和三氧化二砷组成的治疗方案在未进行输血的情况下取得了成功。

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