Cancer Resource & Education Center, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; Department of Psychiatry, Faculty of Medicine & Health Sciences, Universiti Putra Malaysia, Serdang, Selangor, Malaysia.
Cancer Resource & Education Center, Universiti Putra Malaysia, Serdang, Selangor, Malaysia; Department of Public Health, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
Patient Educ Couns. 2018 May;101(5):862-871. doi: 10.1016/j.pec.2018.01.004. Epub 2018 Jan 5.
The aim of this study was to implement and evaluate the outcomes of chemotherapy counselling based on the "Managing Patients on Chemotherapy" module on self-esteem and psychological affect (anxiety, depression) of cancer patients by pharmacists in ten selected government hospitals in Peninsular Malaysia.
A randomized control trial was conducted among 2120 cancer patients from April 2016 to January 2017 in ten selected government hospitals in Peninsular Malaysia. Cancer patients were randomly assigned to intervention and control groups. The intervention group received chemotherapy counselling by pharmacists based on the "Managing Patients on Chemotherapy" module. The outcomes were assessed at baseline, 1st, 2nd and 3rd follow-ups after counselling. In the course of data analysis; independent sample t-test, chi-square and two-way repeated measures ANOVA were conducted.
Mean scores of self-esteem in the intervention group had significant difference in comparison with those of the control group in the 1st, 2nd and 3rd follow-ups after counselling (P < 0.0001). Also, among those with depression and anxiety at baseline, there was reduction in depression and anxiety scores after the 1st, 2nd and 3rd follow-ups after counselling (p < 0.05).
Repetitive counselling by pharmacists based on the "Managing Patients on Chemotherapy" module had positive effect on improving self-esteem and psychological affect of cancer patients undergoing chemotherapy in Peninsular Malaysia.
This module can be used for all Malaysian cancer patients undergoing chemotherapy to improving self-esteem and psychological affect.
本研究旨在实施并评估药剂师基于“管理化疗患者”模块对马来西亚半岛 10 家选定政府医院癌症患者的自尊和心理影响（焦虑、抑郁）进行化疗咨询的结果。
2016 年 4 月至 2017 年 1 月，在马来西亚半岛 10 家选定的政府医院中，对 2120 名癌症患者进行了一项随机对照试验。将癌症患者随机分配到干预组和对照组。干预组接受基于“管理化疗患者”模块的化疗咨询。在咨询后的第 1、2 和 3 次随访中评估结果。在数据分析过程中，进行了独立样本 t 检验、卡方检验和双向重复测量方差分析。
与对照组相比，干预组在咨询后的第 1、2 和 3 次随访中的自尊平均得分存在显著差异（P<0.0001）。此外，在基线时患有抑郁和焦虑的患者中，在咨询后的第 1、2 和 3 次随访中，抑郁和焦虑评分均有所降低（p<0.05）。
药剂师基于“管理化疗患者”模块的重复咨询对改善马来西亚半岛接受化疗的癌症患者的自尊和心理影响有积极作用。
该模块可用于所有在马来西亚接受化疗的癌症患者，以改善其自尊和心理影响。
