Fischer C, Ibañez V, Mauguiere F
Presse Med. 1985 Nov 2;14(37):1914-8.
Brainstem auditory evoked potentials (BAEP) were monitored during 37 neurosurgical operations (acoustic neurinomas with preoperative useful hearing, microvascular decompression of cranial nerves for hemispasm or trigeminal neuralgia, cerebellopontine angle tumors other than acoustic neurinomas, brainstem tumors and posterior circulation surgery). Intraoperative BAEPs were unchanged in 13 patients. Transient BAEP alterations (delay of I-V interval, transient obliteration of BAEP for as long as 8 minutes and 20 minutes) were seen in 13 other patients; irreversible BAEP alterations (loss of evoked response in 6 patients, delay of I-V interval) were seen in 11 patients. BAEP stability or alterations have been correlated with the ongoing surgical maneuver, the neurological outcome and the postoperative auditory function. BAEPs were found to be good predictors of post-operative auditory function but poorer predictors of neurological outcome. Some alterations are strictly associated with surgical retraction or with eighth nerve manipulation either immediately after the surgical maneuver or several minutes later. No detectable cause of BAEP changes was found in a few cases. The value of this monitoring is discussed. It may also help elucidate the mechanisms of hearing loss in acoustic neurinoma surgery.
在37例神经外科手术(术前尚有听力的听神经瘤、因面肌痉挛或三叉神经痛行颅神经微血管减压术、听神经瘤以外的桥小脑角肿瘤、脑干肿瘤及后循环手术)过程中监测脑干听觉诱发电位(BAEP)。13例患者术中BAEP无变化。另外13例患者出现BAEP短暂改变(I-V间期延长、BAEP短暂消失长达8分钟和20分钟);11例患者出现不可逆BAEP改变(6例患者诱发电位消失、I-V间期延长)。BAEP的稳定性或改变与正在进行的手术操作、神经功能转归及术后听觉功能相关。发现BAEP是术后听觉功能的良好预测指标,但对神经功能转归的预测较差。一些改变与手术牵拉或手术操作后即刻或数分钟后的第八神经操作密切相关。少数病例未发现BAEP改变的可检测原因。讨论了这种监测的价值。它也可能有助于阐明听神经瘤手术中听力丧失的机制。