Frood Russell, McDermott Garry, Scarsbrook Andrew
1 Department of Nuclear Medicine, Leeds Teaching Hospitals NHS Trust , Leeds , United Kingdom.
2 Department of Medical Physics & Engineering, Leeds Teaching Hospitals NHS Trust , Leeds , United Kingdom.
Br J Radiol. 2018 Jun;91(1086):20170640. doi: 10.1259/bjr.20170640. Epub 2018 Feb 5.
2-deoxy-2-(Fluorine)-fluoro-D-glucose (FDG) PET/CT is an integral part of lung carcinoma staging and frequently used in the assessment of solitary pulmonary nodules. However, a limitation of conventional three-dimensional PET/CT when imaging the thorax is its susceptibility to motion artefact, which blurs the signal from the lesion resulting in inaccurate representation of size and metabolic activity. Respiratory gated (four-dimensional) PET/CT aims to negate the effects of motion artefact and provide a more accurate interpretation of pulmonary nodules and lymphadenopathy. There have been recent advances in technology and a shift from traditional hardware to more streamlined software methods for respiratory gating which should allow more widespread use of respiratory-gating in the future. The purpose of this article is to review the evidence surrounding four-dimensional PET/CT in pulmonary lesion characterisation.
2-脱氧-2-（氟）氟代-D-葡萄糖（FDG）PET/CT是肺癌分期不可或缺的一部分，常用于孤立性肺结节的评估。然而，传统的三维PET/CT在胸部成像时存在一个局限性，即它容易受到运动伪影的影响，这会使病变信号模糊，导致对病变大小和代谢活性的呈现不准确。呼吸门控（四维）PET/CT旨在消除运动伪影的影响，更准确地解读肺结节和淋巴结病变。近年来技术有了进步，呼吸门控从传统硬件方法转向了更简化的软件方法，这有望在未来使呼吸门控得到更广泛的应用。本文旨在综述有关四维PET/CT在肺部病变特征描述方面的证据。
