Lumbreras-Marquez Jesus, Castillo-Reyther Roberto Arturo, De-la-Maza-Labastida Salvador, Vazquez-Alaniz Fernando
Gynaecology & Obstetric Department. Hospital Central "Dr. Ignacio Morones Prieto". Health Ministry of San Luis Potosi, Avenida Venustiano Carranza #2395, Zona Universitaria, 78290, San Luis, SLP, Mexico.
Clinical laboratory department, Hospital General 450. Health Ministry of Durango, Blvd. Jose Maria Patoni #403, Col. El Cipres, 34206, Durango, DGO, Mexico.
J Med Case Rep. 2018 Jan 17;12(1):12. doi: 10.1186/s13256-017-1534-6.
Takayasu arteritis is a rare, chronic, granulomatous systemic vasculitis of unknown etiology and a few cases have been reported in pregnancy. In pregnancies concomitant with Takayasu arteritis or after diagnosis, Takayasu arteritis negatively affects pregnancy by increasing 13-fold the odds of complications such as hypertensive disorders. The best recommendations in this scenario are still to be made.
We present a case of 21-year-old, gravid 1, Mexican woman of Mestizo descent with chronic hypertension diagnosed since she was 15-years old who presented severe hypertension during pregnancy (early second trimester); the diagnosis of hypertensive disorder of pregnancy was ruled out requiring first-line and second-line antihypertensive therapy without serious associated maternal or fetal morbidity.
Takayasu arteritis and pregnancy play an important role in maternal and fetal outcomes. Efforts should be made to further investigate the Takayasu arteritis diagnosis in pregnant women with refractory hypertension.
大动脉炎是一种罕见的、慢性的、病因不明的肉芽肿性系统性血管炎，孕期报道的病例较少。在合并大动脉炎的妊娠期间或诊断后，大动脉炎会使高血压疾病等并发症的发生几率增加13倍，从而对妊娠产生负面影响。目前在这种情况下仍有待给出最佳建议。
我们报告一例21岁、孕1产0、有梅斯蒂索血统的墨西哥女性病例，该女性自15岁起被诊断为慢性高血压，孕期（孕中期早期）出现严重高血压；排除了妊娠高血压疾病的诊断，需要一线和二线降压治疗，且未出现严重的母婴相关发病情况。
大动脉炎和妊娠对母婴结局起着重要作用。应努力进一步研究难治性高血压孕妇的大动脉炎诊断情况。
