Olbert F, Ogris E, Muzika N, Schlegl A, Vacariu O, Diez W
Wien Klin Wochenschr Suppl. 1985;163:3-15.
The paper reports the results obtained by percutaneous transluminal angioplasty (PTA) in the treatment of renal artery stenosis in 25 patients with secondary hypertension and discusses indications and the technique used. The follow-up period ranged from 0.5 to 12 months. All interventions were performed with the Olbert catheter system. Following PTA a significant decrease in systolic, diastolic and mean arterial pressure was observed in nearly all patients. The response of the plasma renin activity (PRA) to orthostatic stimulation and pharmacological stimulation by furosemide was determined in a subset of 15 patients before and after PTA. A significant decrease in both basal and stimulated PRA values was observed subsequent to PTA. The decrease in PRA values after successful PTA did not, however, correlate with the extent of the blood pressure changes.
本文报道了经皮腔内血管成形术（PTA）治疗25例继发性高血压患者肾动脉狭窄的结果，并讨论了适应证及所采用的技术。随访时间为0.5至12个月。所有干预均使用奥尔伯特导管系统进行。PTA术后，几乎所有患者的收缩压、舒张压和平均动脉压均显著下降。在15例患者的亚组中，于PTA前后测定了血浆肾素活性（PRA）对体位性刺激和速尿药物刺激的反应。PTA后观察到基础和刺激后的PRA值均显著下降。然而，成功的PTA术后PRA值的下降与血压变化的程度无关。
