Center for Outcomes Research and Evaluation, Maine Medical Center Research Institute, Portland, Maine.
Center for Outcomes Research and Evaluation, Maine Medical Center Research Institute, Portland, Maine.
Am J Prev Med. 2018 Mar;54(3):376-384. doi: 10.1016/j.amepre.2017.11.011. Epub 2018 Jan 12.
Reducing the burden of death from cardiovascular disease includes risk factor reduction and medical interventions.
This was an observational analysis at the hospital service area (HSA) level, to examine regional variation and relationships between behavioral risks, health services utilization, and cardiovascular disease mortality (the outcome of interest). HSA-level prevalence of cardiovascular disease behavioral risks (smoking, poor diet, physical inactivity) were calculated from the Behavioral Risk Factor Surveillance System; HSA-level rates of stress tests, diagnostic cardiac catheterization, and revascularization from a statewide multi-payer claims data set from Maine in 2013 (with 606,260 patients aged ≥35 years), and deaths from state death certificate data. Analyses were done in 2016.
There were marked differences across 32 Maine HSAs in behavioral risks: smoking (12.4%-28.6%); poor diet (43.6%-73.0%); and physical inactivity (16.4%-37.9%). After adjustment for behavioral risks, rates of utilization varied by HSA: stress tests (28.2-62.4 per 1,000 person-years, coefficient of variation=17.5); diagnostic cardiac catheterization (10.0-19.8 per 1,000 person-years, coefficient of variation=17.3); and revascularization (4.6-6.2 per 1,000 person-years; coefficient of variation=9.1). Strong HSA-level associations between behavioral risk factors and cardiovascular disease mortality were observed: smoking (R=0.52); poor diet (R=0.38); and physical inactivity (R=0.35), and no association between revascularization and cardiovascular disease mortality after adjustment for behavioral risk factors (R=0.02). HSA-level behavioral risk factors were also strongly associated with all-cause mortality: smoking (R=0.57); poor diet (R=0.49); and physical inactivity (R=0.46).
There is substantial regional variation in behavioral risks and cardiac utilization. Behavioral risk factors are associated with cardiovascular disease mortality regionally, whereas revascularization is not. Efforts to reduce cardiovascular disease mortality in populations should focus on prevention efforts targeting modifiable risk factors.
降低心血管疾病导致的死亡率包括降低风险因素和医疗干预。
这是一项在医院服务区(HSA)层面进行的观察性分析,旨在研究行为风险、卫生服务利用与心血管疾病死亡率(关注的结果)之间的区域差异和关系。从行为风险因素监测系统中计算 HSA 层面心血管疾病行为风险(吸烟、不良饮食、身体活动不足)的流行率;从 2013 年缅因州全州多付款索赔数据集中(606,260 名年龄≥35 岁的患者)计算 HSA 层面压力测试、诊断性心脏导管检查和血运重建的比率,以及从州死亡证明数据中计算死亡率。分析于 2016 年进行。
在缅因州的 32 个 HSA 中,行为风险存在明显差异:吸烟(12.4%-28.6%);不良饮食(43.6%-73.0%);身体活动不足(16.4%-37.9%)。在调整行为风险后,利用率因 HSA 而异:压力测试(28.2-62.4 次/1000 人年,变异系数=17.5);诊断性心脏导管检查(10.0-19.8 次/1000 人年,变异系数=17.3);血运重建(4.6-6.2 次/1000 人年;变异系数=9.1)。观察到行为风险因素与心血管疾病死亡率之间存在强烈的 HSA 水平关联:吸烟(R=0.52);不良饮食(R=0.38);身体活动不足(R=0.35),而在调整行为风险因素后,血运重建与心血管疾病死亡率之间没有关联(R=0.02)。HSA 层面的行为风险因素也与全因死亡率密切相关:吸烟(R=0.57);不良饮食(R=0.49);身体活动不足(R=0.46)。
行为风险和心脏利用存在显著的区域差异。行为风险因素与心血管疾病死亡率存在区域相关性,而血运重建则没有。针对可改变风险因素的预防措施应成为人群降低心血管疾病死亡率的重点。