Tichomirov E D, Mamontova T N, Turchinskaia M V, Burkin V S, Ibragimov F Kh
Zh Mikrobiol Epidemiol Immunobiol. 1985 Sep(9):40-6.
In the study of 255 V. cholerae strains unrelated to vibrio O group I (NAG vibrios), which were isolated from water bodies in the region of the Volga delta in 1977-1982, antibioticograms of 17 types were obtained and R factor was detected in 37.7% of the strains under study. The pronounced heterogeneity of NAG vibrio populations, evaluated in minimal inhibitory concentration (MIC) values with respect to different antibiotics, is specifically manifested by the presence of various dominating subpopulations of these microorganisms, depending on their sensitivity to some chemical drugs. Various representatives of the genus Vibrio were used as a model for demonstrating the ability of the microbial population to enhance its variability as regards MIC values with a seasonal rise in the number of microorganisms.
在对1977年至1982年从伏尔加河三角洲地区水体中分离出的255株与霍乱弧菌O1群无关的霍乱弧菌菌株（非O1群霍乱弧菌）的研究中，获得了17种类型的抗生素谱，在所研究的菌株中有37.7%检测到R因子。非O1群霍乱弧菌群体在对不同抗生素的最低抑菌浓度（MIC）值方面表现出明显的异质性，具体表现为这些微生物存在各种占主导地位的亚群，这取决于它们对某些化学药物的敏感性。以弧菌属的各种代表作为模型，来证明微生物群体在微生物数量随季节增加时，其MIC值变异性增强的能力。
