Department of Dermatology MetroHealth Medical Center, Case Western Reserve University School of Medicine, Cleveland, Ohio.
David Geffen School of Medicine at the University of California, Los Angeles, California.
J Am Acad Dermatol. 2018 May;78(5):983-988.e4. doi: 10.1016/j.jaad.2018.01.009. Epub 2018 Jan 12.
There is a paucity of data providing direct comparison of outcomes, complications, and costs between general and local anesthesia in cutaneous surgery.
Analyze the literature from dermatologic and other specialties to compare outcomes, risks, and costs of general and local anesthesia.
A retrospective analysis of case comparison studies from other specialties comparing outcomes, risks, and/or costs in local versus general anesthesia was performed. A review of the literature from dermatology and other specialties was included.
A total of 51 studies were selected; 41 of them directly examined outcomes in procedures performed under local and general anesthesia, and none found a significant difference in outcomes. A total of 41 studies measured adverse effects. Of these, 15 studies (36.6%) report significantly better outcomes between the 2 techniques. Only 2 studies (4.9%) report significantly improved outcomes with use of general anesthesia; 15 of 36 studies (41.7%) report fewer adverse events in local anesthesia. Of the 13 studies that examined costs, all (100%) found significantly decreased costs with use of local anesthesia.
These data cannot be seamlessly applied to all cases of cutaneous surgery.
Local anesthesia techniques provide outcomes equal to or better than general anesthesia and with significantly lower costs.
目前,关于皮肤外科中全身麻醉与局部麻醉的结果、并发症和成本的直接比较数据较少。
分析皮肤科和其他专业的文献,比较全身麻醉和局部麻醉的结果、风险和成本。
对其他专业的病例对照研究进行回顾性分析,比较局部麻醉与全身麻醉的结果、风险和/或成本。同时还包括对皮肤科和其他专业文献的综述。
共选择了 51 项研究;其中 41 项直接检查了在局部和全身麻醉下进行的手术的结果,没有一项研究发现结果有显著差异。共 41 项研究测量了不良反应。其中,15 项研究(36.6%)报告两种技术之间的结果有显著改善。只有 2 项研究(4.9%)报告全身麻醉的结果显著改善;36 项研究中有 15 项(41.7%)报告局部麻醉的不良事件更少。在 13 项研究成本的研究中,所有(100%)研究都发现使用局部麻醉可显著降低成本。
这些数据不能无缝应用于所有皮肤外科手术。
局部麻醉技术提供的结果与全身麻醉相当或更好,且成本显著降低。