Meier B, Rutishauser W
Acta Med Scand Suppl. 1985;701:142-7. doi: 10.1111/j.0954-6820.1985.tb08898.x.
Since its introduction in 1977 by Grüntzig, percutaneous transluminal coronary angioplasty (PTCA) has been increasingly applied to the treatment of coronary artery disease manifested by symptomatic ischemia. Initially only recommended for proximal short stenoses of one major coronary artery, the indication for PTCA has gradually been enlarged. Today even distally situated coronary stenoses in more than one vessel can be dilated successfully by using a steerable system. In experienced hands, an immediate improvement can be achieved in about 90% of the patients. In the realm of cost and morbidity PTCA offers obvious advantages over bypass surgery. However, indications for PTCA are more restricted than those for bypass surgery, specially in multi-vessel disease where the application of PTCA is still controversial. Moreover, long-term results are less favourable after PTCA since 25-30% of the patients show a recurrence within 6 to 12 months. Although PTCA will not replace coronary bypass surgery, it is already established as an alternative and complementary method for coronary revascularization.
自1977年由格鲁恩齐格引入以来,经皮腔内冠状动脉成形术(PTCA)已越来越多地应用于有症状性心肌缺血表现的冠状动脉疾病的治疗。最初,PTCA仅推荐用于单支主要冠状动脉的近端短段狭窄,其适应证已逐渐扩大。如今,通过使用可操纵系统,多支血管中远段的冠状动脉狭窄也能成功扩张。在经验丰富的医生手中,约90%的患者可实现即刻改善。在成本和发病率方面,PTCA相较于搭桥手术具有明显优势。然而,PTCA的适应证比搭桥手术更受限,特别是在多支血管病变中,PTCA的应用仍存在争议。此外,PTCA后的长期效果较差,因为25%至30%的患者在6至12个月内会出现复发。虽然PTCA不会取代冠状动脉搭桥手术,但它已成为冠状动脉血运重建的一种替代和补充方法。