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全关节置换患者与骨科创伤患者相比发生深静脉血栓的风险:对新预防指南的需求。

The risk of deep vein thrombosis in total joint patients compared to orthopaedic trauma patients: Need for new prevention guidelines.

作者信息

Shen Michelle, Cutrera Norele J, Dodd Ashley C, Wallace Christopher, Avilucea Frank R, Melbourne Craig, Jahangir Alex A, Mir Hassan H, Obremskey William T, Sethi Manish K

机构信息

The Vanderbilt Orthopaedic Institute Center for Health Policy, 1215 21st Avenue South, Suite 4200, Medical Center East, South Tower, Nashville, TN 37292, United States.

出版信息

J Clin Orthop Trauma. 2017 Nov;8(Suppl 2):S52-S56. doi: 10.1016/j.jcot.2016.12.007. Epub 2017 Jan 10.

Abstract

BACKGROUND

The development of Deep Vein Thrombosis (DVT) is a major concern following orthopaedic surgery. No study has yet to compare the rate and risk factors for DVT between total joint and orthopaedic trauma patients. To evaluate if DVT prophylaxis for trauma should differ from total joints, we explored the rate and risk factors for DVT between both cohorts.

METHODS

Using a CPT code search from 2005 to 2013 in the ACS-NSQIP database, 150,657 orthopaedic total joint patients and 44,594 orthopaedic trauma patients were identified. DVT complications, patient demographics, preoperative comorbidities, and surgical characteristics were collected for each patient. A chi-squared test was used to compare the risk factors for DVT between orthopaedic trauma and total joint patients. A multivariable logistic regression model was built to adjust for comorbidities for each cohort.

RESULTS

The rate of DVT diagnosis in the total joint population was 0.8% (N = 1186) and 0.98% (N = 432) in the orthopaedic trauma population (p = 0.57). After controlling for individual comorbidities, dyspnea, peripheral vascular disease, and renal failure were significant risk factors for DVT in total joint patients (p < 0.05), whereas age, ascites and steroid use were significant risk factors for DVT in orthopaedic trauma patients (p < 0.05).

CONCLUSIONS

Historically, the risks for DVT in total joints have been emphasized, yet based on our results, the incidence of DVT is the same for orthopaedic trauma. However, the risk factors varied. It is therefore important to consider specialty-specific DVT prophylaxis for orthopaedic trauma patients in order to improve care and reduce postoperative complications.

摘要

背景

深静脉血栓形成(DVT)的发生是骨科手术后的一个主要问题。尚无研究比较全关节置换患者与骨科创伤患者发生DVT的发生率及危险因素。为评估创伤患者的DVT预防措施是否应与全关节置换患者不同,我们探究了这两组患者发生DVT的发生率及危险因素。

方法

通过在ACS-NSQIP数据库中使用2005年至2013年的CPT编码搜索,确定了150657例骨科全关节置换患者和44594例骨科创伤患者。收集了每位患者的DVT并发症、患者人口统计学资料、术前合并症及手术特征。采用卡方检验比较骨科创伤患者与全关节置换患者发生DVT的危险因素。建立多变量逻辑回归模型以调整每组患者的合并症。

结果

全关节置换患者中DVT诊断率为0.8%(N = 1186),骨科创伤患者中为0.98%(N = 432)(p = 0.57)。在控制个体合并症后,呼吸困难、外周血管疾病和肾衰竭是全关节置换患者发生DVT的显著危险因素(p < 0.05),而年龄、腹水和使用类固醇是骨科创伤患者发生DVT的显著危险因素(p < 0.05)。

结论

以往一直强调全关节置换患者发生DVT的风险,但根据我们的结果,骨科创伤患者DVT的发生率与之相同。然而,危险因素有所不同。因此,考虑针对骨科创伤患者采取特定专科的DVT预防措施对于改善治疗及减少术后并发症很重要。

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