Rehman Suhailur, Arif S H, Kumar Amit, Khan A Q
Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Hind Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Int J Hematol Oncol Stem Cell Res. 2017 Oct 1;11(4):301-304.
Nowadays, the prevalence of Multiple Myeloma (MM) seems to have been increasing among young females. Here, we report that thalidomide is contraindicated in pregnant women diagnosed with MM and those desirous of subsequent pregnancy. In this case report, we compared the clinical response of Thalidomide-Dexamethasone therapy in a post-abortive woman with persistently elevated β-hCG levels due to retained products of conception, undergoing hysterectomy later. This case report underlines the clinical significance of age, the effect of Thalidomide-Dexamethasone therapy even after initial discontinuation and the response to high β-hCG levels.
如今，多发性骨髓瘤（MM）在年轻女性中的患病率似乎一直在上升。在此，我们报告，沙利度胺对诊断为MM的孕妇以及那些希望后续怀孕的女性是禁忌的。在本病例报告中，我们比较了沙利度胺-地塞米松疗法对一名流产后因妊娠物残留导致β-hCG水平持续升高、随后接受子宫切除术的女性的临床反应。本病例报告强调了年龄的临床意义、沙利度胺-地塞米松疗法即使在最初停药后的效果以及对高β-hCG水平的反应。
