Broom N D, Marra D L
Connect Tissue Res. 1985;14(1):1-8. doi: 10.3109/03008208509089838.
The construction and function of a model of articular cartilage based on a system of deformable elements trapped within a three-dimensional network of fibrils is described. The network is generated from a radial array of elements appropriately crosslinked along their length. The model demonstrates in a qualitative sense how a soft composite tissue structure such as articular cartilage developed from a specific arrangement of two primary components exhibiting totally contrasting mechanical properties, i.e. tension resisting collagen fibrils and highly deformable hydrated proteoglycans, can have dimensional stability in its unloaded state and mechanical resilience under a wide range of loading conditions.
本文描述了一种基于被困在三维纤维网络中的可变形元件系统构建的关节软骨模型及其功能。该网络由沿其长度方向适当交联的元件径向阵列生成。该模型从定性角度展示了一种柔软的复合组织结构，如关节软骨，是如何由两种具有截然不同力学性能的主要成分（即抗张的胶原纤维和高度可变形的水合蛋白聚糖）的特定排列发育而来的，以及它如何在未加载状态下具有尺寸稳定性，并在广泛的加载条件下具有力学弹性。
